Analysis of DNA protection, interaction and antimicrobial activity of isatin derivatives.
Sign Up to like & getrecommendations! Published in 2019 at "International journal of biological macromolecules"
DOI: 10.1016/j.ijbiomac.2018.09.084
Abstract: Isatin, thiosemicarbazone and their derivatives have been widely used in biological applications such as antimicrobial, antiviral and anticancer therapies. Herein, eight isatin and thiosemicarbazone derivative compounds were re-synthesized and evaluated for DNA binding analysis including… read more here.
Keywords: dna; dna protection; antimicrobial activity; isatin thiosemicarbazone ... See more keywords
PA-Int5: An isatin-thiosemicarbazone derivative that exhibits anti-nociceptive and anti-inflammatory effects in Swiss mice
Sign Up to like & getrecommendations! Published in 2021 at "Biomedical Reports"
DOI: 10.3892/br.2021.1437
Abstract: Pain and inflammation are symptoms of various diseases, and they can be modulated by different pathways, thus highlighting the importance of investigating the therapeutic effects of novel compounds. Previous studies have shown that isatin-thiosemicarbazone exhibits… read more here.
Keywords: anti inflammatory; int5; isatin thiosemicarbazone; anti nociceptive ... See more keywords