Remarkable enhancement of flavonoid production in a co-cultivation system of Isatis tinctoria L. hairy root cultures and immobilized Aspergillus niger
Sign Up to like & getrecommendations! Published in 2018 at "Industrial Crops and Products"
DOI: 10.1016/j.indcrop.2017.12.017
Abstract: Abstract The dried roots of Isatis tinctoria L. are highly traded in the pharmaceutical industry due to their notable anti-influenza efficacy. For the first time, I. tinctoria hairy root cultures (ITHRCs) were co-cultured with two… read more here.
Keywords: aspergillus niger; root cultures; production; tinctoria hairy ... See more keywords
Alkaloid Enantiomers from Isatis tinctoria with Neuroprotective Effects against H2O2-Induced SH-SY5Y Cell Injury.
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DOI: 10.1055/a-1023-8940
Abstract: Six pairs of alkaloid enantiomers including 11 new alkaloids (1A: /1B: -5A: /5B, 6A: ) were isolated from the leaves of Isatis tinctoria. Their structures were established by extensive spectroscopic analyses. Enantiomers were separated successfully… read more here.
Keywords: alkaloid enantiomers; isatis tinctoria; cell injury; h2o2 induced ... See more keywords
Isatisindigoticanine A, a novel indole alkaloid with an unpresented carbon skeleton from the roots of Isatis tinctoria
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DOI: 10.1080/14786419.2019.1644632
Abstract: Abstract Isatisindigoticanine A (1), a new indole alkaloid with an unusual carbon skeleton of a benzofuran-3-one unit connected with a 1H-indole-3-yl unit and a 4-(1,2-dihydroxyethyl)-6-oxa-3-azabicyclo[3.1.0]hexan-2-one unit via a C-3－C-8'' bond and a C-4'－C-8'' bond, was… read more here.
Keywords: carbon skeleton; isatis tinctoria; indole alkaloid; roots isatis ... See more keywords
Four new indole alkaloids from the roots of Isatis tinctoria.
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DOI: 10.1080/14786419.2020.1779716
Abstract: Chemical fractionation of the ethanolic extract of the roots of Isatis tinctoria L. (I. tinctoria) yielded fourteen indole alkaloids including four new ones, isatisindigoticanine L-N and isatindigoside M. Their structures were established on the basis… read more here.
Keywords: roots isatis; alkaloids roots; four new; indole alkaloids ... See more keywords
A focused natural compound screen reveals senolytic and senostatic effects of Isatis tinctoria
Sign Up to like & getrecommendations! Published in 2022 at "Animal Cells and Systems"
DOI: 10.1080/19768354.2022.2143895
Abstract: ABSTRACT Natural products and their derivatives historically represent alternatives to conventional synthetic molecules for pharmacotherapy, ranging from cancer chemotherapeutics to cosmetic ingredients that exert anti-aging activities. Cellular senescence is considered a main driver of skin… read more here.
Keywords: skin; compound screen; senescence; woad extracts ... See more keywords
Microscopic Mass Spectrometry Imaging Reveals the Distribution of Phytochemicals in the Dried Root of Isatis tinctoria
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DOI: 10.3389/fphar.2021.685575
Abstract: The dried root of Isatis tinctoria L. (Brassicaceae) is one of the most popular traditional Chinese medicines with well-recognized prevention and treatment effects against viral infections. Above 300 components have been isolated from this herb,… read more here.
Keywords: mass spectrometry; root; isatis tinctoria; root isatis ... See more keywords
In Vitro Anthelmintic Activity of Isatis tinctoria Extracts against Ewes’ Gastrointestinal Nematodes (GINs), a Possible Application for Animal Welfare
Sign Up to like & getrecommendations! Published in 2022 at "Veterinary Sciences"
DOI: 10.3390/vetsci9030129
Abstract: Sheep gastrointestinal nematode (GIN) infestation represents a limiting factor for sheep farming and milk production in Italy. The development of anthelmintic resistance to conventionally used drugs suggests the path towards the use of natural remedies… read more here.
Keywords: tinctoria extracts; vitro anthelmintic; isatis tinctoria; anthelmintic activity ... See more keywords