Isavuconazole plasma concentrations in critically ill patients during extracorporeal membrane oxygenation
Sign Up to like & getrecommendations! Published in 2022 at "Journal of Antimicrobial Chemotherapy"
DOI: 10.1093/jac/dkac196
Abstract: Abstract Background Isavuconazole is an antifungal drug used for treatment of invasive fungal infections. Critically ill COVID-19 and influenza patients require extracorporeal membrane oxygenation (ECMO) in cases with severe acute respiratory distress syndrome and have… read more here.
Keywords: isavuconazole; critically ill; isavuconazole plasma; plasma concentrations ... See more keywords
Studies on the inhibitory effect of isavuconazole on flumatinib metabolism in vitro and in vivo
Sign Up to like & getrecommendations! Published in 2023 at "Frontiers in Pharmacology"
DOI: 10.3389/fphar.2023.1168852
Abstract: As the validated agent for the treatment of chronic myelogenous leukemia (CML), flumatinib is a novel oral tyrosine kinase inhibitor (TKI) with higher potency and selectivity for BCR-ABL1 kinase compared to imatinib. Many patients experience… read more here.
Keywords: vitro vivo; isavuconazole; flumatinib metabolism; liver microsomes ... See more keywords
In Vitro Interaction between Isavuconazole and Tacrolimus, Cyclosporin A, or Sirolimus against Aspergillus Species
Sign Up to like & getrecommendations! Published in 2020 at "Journal of Fungi"
DOI: 10.3390/jof6030103
Abstract: The interaction of isavuconazole with immunosuppressors (tacrolimus, cyclosporin A, or sirolimus) against 30 Aspergillus isolates belonging to the most common species responsible for invasive aspergillosis in humans (Aspergillus flavus, Aspergillus fumigatus, Aspergillus nidulans, Aspergillus niger,… read more here.
Keywords: tacrolimus cyclosporin; cyclosporin sirolimus; isavuconazole; isavuconazole tacrolimus ... See more keywords
Synergistic In Vitro Interaction of Isavuconazole and Isoquercitrin against Candida glabrata
Sign Up to like & getrecommendations! Published in 2022 at "Journal of Fungi"
DOI: 10.3390/jof8050525
Abstract: In vitro interactions of broad-spectrum azole isavuconazole with flavonoid isoquercitrin were evaluated by a broth microdilution checkerboard technique based on the European Committee on Antimicrobial Susceptibility Testing (EUCAST) reference methodology for antifungal susceptibility testing against… read more here.
Keywords: interaction; isavuconazole; synergistic vitro; candida ... See more keywords