Knockdown of XIST up‐regulates 263294miR‐340‐5p to relieve myocardial ischaemia–reperfusion injury via inhibiting cyclin D1
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DOI: 10.1002/ehf2.13766
Abstract: Long non‐coding RNAs (lncRNAs) are known to participate in various human diseases, while the role of X inactive‐specific transcript (XIST) binding microRNA‐340‐5p (miR‐340‐5p) remains seldom studied. We aim to identify the role of the XIST/miR‐340‐5p/cyclin… read more here.
Keywords: xist; ischaemia reperfusion; reperfusion injury; myocardial ischaemia ... See more keywords
Berberine up‐regulates miR‐340‐5p to protect myocardial ischaemia/reperfusion from HMGB1‐mediated inflammatory injury
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DOI: 10.1002/ehf2.14235
Abstract: Myocardial ischaemia/reperfusion injury (MIRI) is a major cause of heart failure after myocardial infarction. Berberine (BBR) presents anti‐inflammatory and immunosuppressive properties in many diseases. Our research looked into the therapeutic effects and mechanism of BBR… read more here.
Keywords: ischaemia reperfusion; injury; myocardial ischaemia; berberine ... See more keywords
The Role of Extracellular DNA and Histones in Ischaemia-Reperfusion Injury of the Myocardium
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DOI: 10.1007/s10557-020-06946-6
Abstract: Despite an increase in the rates of survival in patients suffering myocardial infarction, as yet there is no therapy specifically targeting ischaemia and reperfusion injury of the myocardium. With a greater understanding of immune activation… read more here.
Keywords: dna; myocardium; role; ischaemia reperfusion ... See more keywords
Changes in Mitochondria-Associated Protein Expression and Mitochondrial Function in Response to 2 Weeks of Enriched Environment Training After Cerebral Ischaemia-Reperfusion Injury
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DOI: 10.1007/s12031-019-01428-3
Abstract: An enriched environment (EE) can stimulate the recovery of neurological function following a cerebral ischaemia-reperfusion injury; however, the impact of EE’s on mitochondrial function has been insufficiently studied. Our research aimed to assess whether EE’s… read more here.
Keywords: protein expression; cerebral ischaemia; group; ischaemia reperfusion ... See more keywords
Dexmedetomidine protects against myocardial ischaemia/reperfusion-induced renal damage in rats
Sign Up to like & getrecommendations! Published in 2018 at "Egyptian Journal of Anaesthesia"
DOI: 10.1016/j.egja.2017.09.005
Abstract: Abstract Background Myocardial ischaemia/reperfusion (MI/R) may induce renal damage. Our aim was to investigate the effects of dexmedetomidine (DEX) administration at two different timings either before or after ischaemia on renal damage induced by MI/R.… read more here.
Keywords: reperfusion; myocardial ischaemia; renal damage; ischaemia reperfusion ... See more keywords
Effects of metformin on the heart with ischaemia-reperfusion injury: Evidence of its benefits from in vitro, in vivo and clinical reports.
Sign Up to like & getrecommendations! Published in 2019 at "European journal of pharmacology"
DOI: 10.1016/j.ejphar.2019.172489
Abstract: Ischaemia reperfusion (I/R) injury following myocardial infarction reperfusion therapy is a phenomenon that results in further loss of cardiomyocytes and cardiac contractility. Among the potential therapeutics to counter cardiac I/R injury, the antidiabetic drug metformin… read more here.
Keywords: vitro vivo; clinical reports; reperfusion; ischaemia reperfusion ... See more keywords
Therapeutic activity of superoxide dismutase‐containing enzymosomes on rat liver ischaemia‐reperfusion injury followed by magnetic resonance microscopy
Sign Up to like & getrecommendations! Published in 2017 at "European Journal of Pharmaceutical Sciences"
DOI: 10.1016/j.ejps.2017.09.008
Abstract: &NA; Liver ischaemia‐reperfusion injury (IRI) may occur during hepatic surgery and is unavoidable in liver transplantation. Superoxide dismutase enzymosomes (SOD‐enzymosomes), liposomes where SOD is at the liposomal surface expressing enzymatic activity in intact form without… read more here.
Keywords: microscopy; liver ischaemia; ischaemia reperfusion; reperfusion injury ... See more keywords
A high salt diet aggravates retinal ischaemia/reperfusion injury.
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DOI: 10.1016/j.exer.2019.107784
Abstract: Ischaemia/reperfusion contributes to the pathophysiological process of many retinal diseases. Previous studies have shown that retinal ischaemia/reperfusion mainly results in neuronal degeneration, including thinning of the retina, death of retinal ganglion cells and reduction in… read more here.
Keywords: reperfusion; high salt; ischaemia reperfusion; salt diet ... See more keywords
The beneficial roles of metformin on the brain with cerebral ischaemia/reperfusion injury.
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DOI: 10.1016/j.phrs.2019.104261
Abstract: Cerebral ischaemia/reperfusion (I/R) injury is the transient loss, followed by rapid return, of blood flow to the brain. This condition is often caused by strokes and heart attacks. The underlying mechanisms resulting in brain damage… read more here.
Keywords: cerebral ischaemia; cerebral injury; brain; ischaemia reperfusion ... See more keywords
Mycophenolate mofetil attenuates uterine ischaemia/reperfusion injury in a rat model.
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DOI: 10.1016/j.rbmo.2016.11.007
Abstract: This study evaluated the effect of mycophenolate mofetil (MMF) on uterine tissue preservation following ischaemia/reperfusion (I/R) injury. Uterine I/R injury was induced in rats by clamping the lower abdominal aorta and ovarian arteries for 30 min.… read more here.
Keywords: uterine tissue; mycophenolate mofetil; group; ischaemia reperfusion ... See more keywords
Hypertrophic preconditioning cardioprotection after myocardial ischaemia/reperfusion injury involves ALDH2-dependent metabolism modulation
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DOI: 10.1016/j.redox.2021.101960
Abstract: Brief episodes of ischaemia and reperfusion render the heart resistant to subsequent prolonged ischaemic insult, termed ischaemic preconditioning. Here, we hypothesized that transient non-ischaemic stress by hypertrophic stimulation would induce endogenous cardioprotective signalling and enhance… read more here.
Keywords: metabolism; tac preconditioning; hypertrophic preconditioning; ischaemia reperfusion ... See more keywords