Lesion-Specific Ischemia With Noninvasive Computed Tomographic Angiography: Superior to Conventional Stress Testing?
Sign Up to like & getrecommendations! Published in 2017 at "JAMA cardiology"
DOI: 10.1001/jamacardio.2017.1315
Abstract: For many decades, stress testing has been at the core of the diagnostic evaluation algorithm for detection of obstructive coronary artery disease (CAD) for the patient presenting with stable, suspected ischemic heart disease.1 The underlying… read more here.
Keywords: stress testing; cad; evidence; ischemia ... See more keywords
Association Between Change in Circulating Progenitor Cells During Exercise Stress and Risk of Adverse Cardiovascular Events in Patients With Coronary Artery Disease.
Sign Up to like & getrecommendations! Published in 2019 at "JAMA cardiology"
DOI: 10.1001/jamacardio.2019.4528
Abstract: Importance Stem and progenitor cells mobilize from the bone marrow in response to myocardial ischemia. However, the association between the change in circulating progenitor cell (CPC) counts and disease prognosis among patients with ischemia is… read more here.
Keywords: change; stress; ischemia; progenitor ... See more keywords
Ischemic Microenvironment-Responsive Therapeutics for Cardiovascular Diseases.
Sign Up to like & getrecommendations! Published in 2021 at "Advanced materials"
DOI: 10.1002/adma.202105348
Abstract: Cardiovascular diseases caused by ischemia are attracting considerable attention owing to its high morbidity and mortality worldwide. Although numerous agents with cardioprotective benefits have been identified, their clinical outcomes are hampered by their low bioavailability,… read more here.
Keywords: ischemic microenvironment; microenvironment responsive; responsive therapeutics; cardiovascular diseases ... See more keywords
Cilostazol decreases duration of spreading depolarization and spreading ischemia after aneurysmal subarachnoid hemorrhage
Sign Up to like & getrecommendations! Published in 2018 at "Annals of Neurology"
DOI: 10.1002/ana.25361
Abstract: Traditionally, angiographic vasospasm (aVS) has been thought to cause delayed cerebral ischemia (DCI) after aneurysmal subarachnoid hemorrhage (aSAH). However, successful treatment of aVS alone does not result in improved neurological outcome. Therefore, there may be… read more here.
Keywords: aneurysmal subarachnoid; spreading depolarization; ischemia; subarachnoid hemorrhage ... See more keywords
Compensatory neuromuscular junction adaptations of forelimb muscles in focal cortical ischemia in rats
Sign Up to like & getrecommendations! Published in 2020 at "Brain and Behavior"
DOI: 10.1002/brb3.1472
Abstract: Upper limb movements are affected frequently by brain ischemia (BI). Mechanisms involved in recovery and compensatory movements have developed several studies. However, less attention is given to skeletal muscles, where neuromuscular junction (NMJ) has an… read more here.
Keywords: compensatory neuromuscular; ischemia; neuromuscular junction; junction adaptations ... See more keywords
ISCHEMIA from a clinicians perspective: Treating the patient or the investigator?
Sign Up to like & getrecommendations! Published in 2020 at "Catheterization and Cardiovascular Interventions"
DOI: 10.1002/ccd.28786
Abstract: As clinicians, we are very interested in providing care that improves the quality of our patient's lifestyle and decreases cardiovascular events. As such, the results of the Ischemia Trial, recently presented at the 2019 American… read more here.
Keywords: trial; practice; ischemia; therapy ... See more keywords
The spectrum of angiography‐derived IMR according to morphological and physiological coronary stenosis in patients with suspected myocardial ischemia
Sign Up to like & getrecommendations! Published in 2023 at "Clinical Cardiology"
DOI: 10.1002/clc.23999
Abstract: Coronary microvascular dysfunction is crucial in determining myocardial ischemia; however, the relationship between epicardial coronary diameter stenosis (DS) and the index of microcirculatory resistance (IMR) remains unclear. We sought to explore the distribution of coronary… read more here.
Keywords: ischemia; myocardial ischemia; suspected myocardial; derived imr ... See more keywords
Suppression of SNARE‐dependent exocytosis in retinal glial cells and its effect on ischemia‐induced neurodegeneration
Sign Up to like & getrecommendations! Published in 2017 at "Glia"
DOI: 10.1002/glia.23144
Abstract: Nervous tissue is characterized by a tight structural association between glial cells and neurons. It is well known that glial cells support neuronal functions, but their role under pathologic conditions is less well understood. Here,… read more here.
Keywords: snare dependent; glial cells; dependent exocytosis; ischemia ... See more keywords
Transient astrocyte‐like NG2 glia subpopulation emerges solely following permanent brain ischemia
Sign Up to like & getrecommendations! Published in 2021 at "Glia"
DOI: 10.1002/glia.24064
Abstract: NG2 glia display wide proliferation and differentiation potential under physiological and pathological conditions. Here, we examined these two features following different types of brain disorders such as focal cerebral ischemia (FCI), cortical stab wound (SW),… read more here.
Keywords: astrocyte like; like ng2; ng2 glia; subpopulation ... See more keywords
Coumestrol pre‐treatment improves spatial learning and memory deficits following transient cerebral ischemia recruiting hippocampal GluR2 AMPA receptors
Sign Up to like & getrecommendations! Published in 2022 at "Hippocampus"
DOI: 10.1002/hipo.23418
Abstract: Transient global ischemia is a leading cause of learning and memory dysfunction and induces a pattern of delayed neuronal death in the CA1 subfield of the hippocampus by down‐regulating GluR2 mRNA AMPA receptors in this… read more here.
Keywords: ischemia; ampa receptors; memory deficits; memory ... See more keywords
Eprosartan: A closer insight into its neuroprotective activity in rats with focal cerebral ischemia–reperfusion injury
Sign Up to like & getrecommendations! Published in 2021 at "Journal of Biochemical and Molecular Toxicology"
DOI: 10.1002/jbt.22796
Abstract: Eprosartan (EPRO), an angiotensin receptor type‐1 (AT‐1) blocker, exhibited neuroprotective activities in ischemic stroke resulting from focal cerebral ischemia in rats. The current study aimed to clarify the neuroprotective role of EPRO in middle carotid… read more here.
Keywords: cerebral ischemia; group; focal cerebral; ischemia ... See more keywords