Inhibition of DNA methylation in newborns reprograms ischemia-sensitive biomarkers resulting in development of a heart ischemia-sensitive phenotype late in life.
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DOI: 10.1016/j.reprotox.2021.09.007
Abstract: Adverse environmental stress exposure at critical perinatal stages can alter cardiovascular development, which could persist into adulthood and develop a cardiovascular dysfunctional phenotype late in life. However, the underlying molecular mechanisms remain largely unknown. The… read more here.
Keywords: ischemia sensitive; late life; phenotype late; dna methylation ... See more keywords