Modulation of miR29a improves impaired post-ischemic angiogenesis in hyperglycemia
Sign Up to like & getrecommendations! Published in 2017 at "Experimental Biology and Medicine"
DOI: 10.1177/1535370217716424
Abstract: Individuals with diabetes mellitus suffer from impaired angiogenesis and this contributes to poorer peripheral arterial disease outcomes. In experimental peripheral arterial disease, angiogenesis and perfusion recovery are impaired in mice with diabetes. We recently showed… read more here.
Keywords: angiogenesis; mir29a; post ischemic; ischemic angiogenesis ... See more keywords
m7G Methyltransferase METTL1 Promotes Post-ischemic Angiogenesis via Promoting VEGFA mRNA Translation
Sign Up to like & getrecommendations! Published in 2021 at "Frontiers in Cell and Developmental Biology"
DOI: 10.3389/fcell.2021.642080
Abstract: Post-transcriptional modifications play pivotal roles in various pathological processes and ischemic disorders. However, the role of N7-methylguanosine (m7G), particularly m7G in mRNA, on post-ischemic angiogenesis remains largely unknown. Here, we identified that methyltransferase like 1… read more here.
Keywords: m7g; angiogenesis; post ischemic; ischemic angiogenesis ... See more keywords
Endothelial G protein stimulatory α-subunit is a critical regulator of post-ischemic angiogenesis
Sign Up to like & getrecommendations! Published in 2022 at "Frontiers in Cardiovascular Medicine"
DOI: 10.3389/fcvm.2022.941946
Abstract: Post-ischemic angiogenesis is a vital pathophysiological process in diseases such as peripheral arterial disease (PAD), heart ischemia, and diabetic retinopathy. The molecular mechanisms of post-ischemic angiogenesis are complicated and not fully elucidated. The G protein… read more here.
Keywords: angiogenesis; post ischemic; ischemic angiogenesis; protein stimulatory ... See more keywords
Endothelial S1pr2 regulates post-ischemic angiogenesis via AKT/eNOS signaling pathway
Sign Up to like & getrecommendations! Published in 2022 at "Theranostics"
DOI: 10.7150/thno.71585
Abstract: Aims: It is important to understand the mechanism that regulates post-ischemic angiogenesis and to explore a new therapeutic target for an effective improvement of revascularization in peripheral artery disease (PAD) patients. Post-ischemic angiogenesis is a… read more here.
Keywords: blood; post ischemic; ischemic angiogenesis; s1pr2 ... See more keywords