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Published in 2023 at "JAMA Network Open"
DOI: 10.1001/jamanetworkopen.2023.3770
Abstract: Key Points Question Is higher resource utilization, quantified by hospital costs, associated with survival without neurodevelopmental impairment among infants with hypoxic-ischemic encephalopathy treated with therapeutic hypothermia? Findings In this cohort study of 381 neonates with…
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Keywords:
neurodevelopmental outcomes;
hypoxic ischemic;
neonates hypoxic;
resource utilization ... See more keywords
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Published in 2018 at "Journal of Cellular Biochemistry"
DOI: 10.1002/jcb.28138
Abstract: Long noncoding RNAs (lncRNAs) have been shown to participate in many biological processes. To investigate the expression profiles of lncRNAs and their potential functions in neonatal hypoxic‐ischemic encephalopathy (HIE), we detected the lncRNA and messenger…
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Keywords:
long noncoding;
expression profiles;
hypoxic ischemic;
ischemic encephalopathy ... See more keywords
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Published in 2018 at "Pediatric Radiology"
DOI: 10.1007/s00247-018-4094-z
Abstract: BackgroundPseudonormalization of diffusion-weighted magnetic resonance imaging (MRI) can lead to underestimation of brain injury in newborns with hypoxic–ischemic encephalopathy (HIE), posing a significant problem. We have noticed that some neonates show pseudonormalization negativity on diffusion-weighted…
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Keywords:
diffusion;
hypoxic ischemic;
weighted imaging;
diffusion weighted ... See more keywords
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Published in 2020 at "Archives of Gynecology and Obstetrics"
DOI: 10.1007/s00404-020-05757-2
Abstract: Neonatal hypoxic–ischemic encephalopathy (HIE) in term infants, is a major cause of neonatal mortality and severe neurologic disability. To identify in labor fetal monitoring characteristic patterns and perinatal factors associated with neonatal HIE. Single-center retrospective…
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Keywords:
hypoxic ischemic;
ischemic encephalopathy;
monitoring;
hie ... See more keywords
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Published in 2018 at "Molecular Neurobiology"
DOI: 10.1007/s12035-018-1452-7
Abstract: Neonatal hypoxic-ischemic encephalopathy (HIE) causes serious neurological disability; there are, however, currently few promising therapies for it. We have recently shown that δ-opioid receptor (DOR) is neuroprotective by downregulating TNF-α. Since hypoxia-ischemia (HI) triggers a…
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Keywords:
opioid receptor;
hypoxic ischemic;
dor;
inflammatory ... See more keywords
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Published in 2020 at "Translational Stroke Research"
DOI: 10.1007/s12975-020-00832-x
Abstract: Immune responses to neonatal hypoxic ischemic encephalopathy (HIE) exacerbate brain injury. Phagocytes, including microglia, play a central role in the immune response, but how the activation of phagocytes is regulated remains elusive. Previously, we have…
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Keywords:
irf5;
hypoxic ischemic;
ischemic encephalopathy;
neonatal hypoxic ... See more keywords
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Published in 2018 at "Clinical Neurophysiology"
DOI: 10.1016/j.clinph.2018.03.043
Abstract: OBJECTIVES To assess the prognostic role of evoked potentials (EP) in neonates with normal magnetic resonance imaging (MRI) after therapeutic hypothermia (TH) for hypoxic-ischemic encephalopathy (HIE). METHODS Thirty-five neonates recruited for TH because of HIE,…
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Keywords:
evoked potentials;
hypoxic ischemic;
normal mri;
neonates normal ... See more keywords
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Published in 2017 at "Early human development"
DOI: 10.1016/j.earlhumdev.2017.06.011
Abstract: BACKGROUND Therapeutic hypothermia is known to improve outcomes in neonates with hypoxic ischemic encephalopathy (HIE). There are no studies that have compared servo controlled cooling (SCC) versus manually controlled cooling (MCC) methods in HIE. AIM…
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Keywords:
scc versus;
mcc;
hypoxic ischemic;
neonates hypoxic ... See more keywords
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Published in 2017 at "Early human development"
DOI: 10.1016/j.earlhumdev.2017.07.008
Abstract: BACKGROUND Neurological outcomes in neonatal hypoxic-ischemic encephalopathy (HIE) continue to be sub-optimal despite therapeutic hypothermia (TH). Cerebral near-infrared spectroscopy provides real-time regional oxygen saturation (CrSO2) that may be a marker of adverse MRI findings and…
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Keywords:
hypoxic ischemic;
brain;
ischemic encephalopathy;
mri ... See more keywords
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Published in 2020 at "Journal of obstetrics and gynaecology Canada : JOGC = Journal d'obstetrique et gynecologie du Canada : JOGC"
DOI: 10.1016/j.jogc.2020.04.020
Abstract: INTRODUCTION Neonatal hypoxic-ischemic encephalopathy (HIE) is associated with neonatal mortality, acute neurological injury, and long-term neurodevelopmental disabilities; however, the association between intrapartum factors and HIE remains unclear. METHODS This population-based cohort study used linked obstetrical…
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Keywords:
among infants;
gestation;
weeks gestation;
hypoxic ischemic ... See more keywords
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Published in 2018 at "Jornal de pediatria"
DOI: 10.1016/j.jped.2017.05.009
Abstract: OBJECTIVE To determine if the efficacy of passive hypothermia and adverse events during transport are related to the severity of neonatal hypoxic-ischemic encephalopathy. METHODS This was a retrospective study of 67 infants with hypoxic-ischemic encephalopathy,…
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Keywords:
events transport;
hypothermia;
hypoxic ischemic;
ischemic encephalopathy ... See more keywords