Is hyperhomocysteinemia a causal factor for heart failure? The impact of the functional variants of MTHFR and PON1 on ischemic and non-ischemic etiology.
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DOI: 10.1016/j.ijcard.2016.11.213
Abstract: BACKGROUND Hyperhomocysteinemia was found to be uniformly associated with the development of heart failure (HF) and HF mortality; however, it is uncertain whether this relation is causative or not. We used Mendelian randomization to examine… read more here.
Keywords: ischemic etiology; etiology; hyperhomocysteinemia causal; heart failure ... See more keywords