Post-translational modification patterns on β-myosin heavy chain are altered in ischemic and nonischemic human hearts
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DOI: 10.7554/elife.74919
Abstract: Phosphorylation and acetylation of sarcomeric proteins are important for fine-tuning myocardial contractility. Here, we used bottom-up proteomics and label-free quantification to identify novel post-translational modifications (PTMs) on β-myosin heavy chain (β-MHC) in normal and failing… read more here.
Keywords: ischemic nonischemic; heavy chain; post translational; myosin heavy ... See more keywords