Crystal structure and receptor-interacting residues of MYDGF — a protein mediating ischemic tissue repair
Sign Up to like & getrecommendations! Published in 2019 at "Nature Communications"
DOI: 10.1038/s41467-019-13343-7
Abstract: Myeloid-derived growth factor (MYDGF) is a paracrine-acting protein that is produced by bone marrow-derived monocytes and macrophages to protect and repair the heart after myocardial infarction (MI). This effect can be used for the development… read more here.
Keywords: tissue repair; ischemic tissue; tissue; structure ... See more keywords
Ischemic tissue released microvesicles induce monocyte reprogramming and increase tissue repair by a tissue factor-dependent mechanism.
Sign Up to like & getrecommendations! Published in 2021 at "Cardiovascular research"
DOI: 10.1093/cvr/cvab266
Abstract: AIMS Despite increasing evidence that monocytes may acquire endothelial features, it remains unclear how monocytes participate in angiogenesis after ischemic damage. We investigated whether ischemic cells can release microvesicles (MVs) and promote neovascularisation in a… read more here.
Keywords: induce monocyte; ischemic tissue; tissue factor; tissue ... See more keywords
Absence of Cold-Inducible RNA-Binding Protein (CIRP) Promotes Angiogenesis and Regeneration of Ischemic Tissue by Inducing M2-Like Macrophage Polarization
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DOI: 10.3390/biomedicines9040395
Abstract: Cold-inducible RNA-binding protein (CIRP) is an intracellular RNA-chaperone and extracellular promoter of inflammation, which is increasingly expressed and released under conditions of hypoxia and cold stress. The functional relevance of CIRP for angiogenesis and regeneration… read more here.
Keywords: angiogenesis regeneration; ischemic tissue; rna; regeneration ischemic ... See more keywords
Mesenchymal stem cells in ischemic tissue regeneration
Sign Up to like & getrecommendations! Published in 2023 at "World Journal of Stem Cells"
DOI: 10.4252/wjsc.v15.i2.16
Abstract: Diseases caused by ischemia are one of the leading causes of death in the world. Current therapies for treating acute myocardial infarction, ischemic stroke, and critical limb ischemia do not complete recovery. Regenerative therapies opens… read more here.
Keywords: regeneration; ischemic tissue; mesenchymal stem; cells ischemic ... See more keywords