Articles with "iscr" as a keyword



Cpe1786/IscR of Clostridium perfringens represses expression of genes involved in Fe-S cluster biogenesis.

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Published in 2017 at "Research in microbiology"

DOI: 10.1016/j.resmic.2016.03.002

Abstract: Cpe1786 of Clostridium perfringens is an Rrf2-type regulator containing the three-cysteine residues coordinating a Fe-S in IscR, the repressor controlling Fe-S homeostasis in enterobacteria. The cpe1786 gene formed an operon with iscSU involved in Fe-S… read more here.

Keywords: cpe1786; iscr; clostridium perfringens; expression genes ... See more keywords

Coordination of the Fe-S cluster biogenesis network by the sRNA RyhB in E. coli

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Published in 2025 at "RNA Biology"

DOI: 10.1080/15476286.2025.2570040

Abstract: ABSTRACT Iron (Fe) plays critical roles as enzyme cofactor involved in key biological processes but can also lead to toxicity by catalysing the formation of highly damaging reactive oxygen species. To stabilize Fe and perform… read more here.

Keywords: isc hsc; iscr; cluster; operon ... See more keywords

The Role of the [2Fe‐2S] Cluster of Escherichia coli IscR in Responding to Redox‐Cycling Agents

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Published in 2025 at "Molecular Microbiology"

DOI: 10.1111/mmi.70021

Abstract: The mechanisms by which cells respond to growth inhibitory redox‐cycling agents is only partially understood. In Escherichia coli K12, the IscR regulon, which includes the ISC and SUF Fe‐S cluster biogenesis machineries, is differentially expressed… read more here.

Keywords: iscr; redox cycling; cluster; pms ... See more keywords

Genome Scale Analysis Reveals IscR Directly and Indirectly Regulates Virulence Factor Genes in Pathogenic Yersinia

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Published in 2021 at "mBio"

DOI: 10.1128/mbio.00633-21

Abstract: How bacteria adapt to the changing environment within the host is critical for their ability to survive and cause disease. For example, the mammalian host severely restricts iron availability to limit bacterial growth, referred to… read more here.

Keywords: iron; iscr; yersinia; factor ... See more keywords