Context-dependent responses of Drosophila intestinal stem cells to intracellular reactive oxygen species
Sign Up to like & getrecommendations! Published in 2020 at "Redox Biology"
DOI: 10.1016/j.redox.2020.101835
Abstract: Reactive oxygen species (ROS) contribute to cellular redox environment and serve as signaling molecules. Excessive ROS can lead to oxidative stress that are involved in a broad spectrum of physiological and pathological conditions. Stem cells… read more here.
Keywords: ros; ros levels; stem cells; iscs ... See more keywords
A bone morphogenetic protein signaling inhibitor, LDN193189, converts ischemia-induced multipotent stem cells into neural stem/progenitor cell-like cells.
Sign Up to like & getrecommendations! Published in 2022 at "Stem cells and development"
DOI: 10.1089/scd.2022.0139
Abstract: Stem cell therapy is used to restore neurological function in stroke patients. We have previously reported that ischemia-induced multipotent stem cells (iSCs), which are likely derived from brain pericytes, develop in post-stroke human and mouse… read more here.
Keywords: ischemia induced; multipotent stem; induced multipotent; iscs ... See more keywords
GUCY2C maintains intestinal LGR5+ stem cells by opposing ER stress
Sign Up to like & getrecommendations! Published in 2017 at "Oncotarget"
DOI: 10.18632/oncotarget.22084
Abstract: Long-lived multipotent stem cells (ISCs) at the base of intestinal crypts adjust their phenotypes to accommodate normal maintenance and post-injury regeneration of the epithelium. Their long life, lineage plasticity, and proliferative potential underlie the necessity… read more here.
Keywords: gucy2c; stress; gucy2c mice; stem cells ... See more keywords
Screening and Identification of Key Genes for Activation of Islet Stellate Cell
Sign Up to like & getrecommendations! Published in 2021 at "Frontiers in Endocrinology"
DOI: 10.3389/fendo.2021.695467
Abstract: Background It has been demonstrated that activated islet stellate cells (ISCs) play a critical role in islet fibrogenesis and significantly contribute to the progression of type 2 diabetes mellitus. However, the key molecules responsible for… read more here.
Keywords: key genes; islet stellate; iscs; activation ... See more keywords