Platelets correlate with false negative T-SPOT.TB results by inhibiting interferon-γ production in T cells via degranulation
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DOI: 10.3389/fcimb.2022.937416
Abstract: Background T-SPOT.TB (T-SPOT) is widely used for the detection of Mycobacterium tuberculosis infection by detecting interferon-gamma (IFN-γ) release in T lymphocytes. This assay is performed on peripheral blood mononuclear cells (PBMCs) separated by Ficoll density… read more here.
Keywords: spot; spot assay; iscs positive; production cells ... See more keywords