Decreased RNF41 expression leads to insulin resistance in skeletal muscle of obese women.
Sign Up to like & getrecommendations! Published in 2018 at "Metabolism: clinical and experimental"
DOI: 10.1016/j.metabol.2018.01.014
Abstract: CONTEXT Toll-like receptor 4 (TLR4) activation contributes to obesity-associated insulin resistance in skeletal muscles (SM). TLR4 signaling involves two pathways: the myeloid differentiation primary response gene 88 (MyD88) leading to inflammatory cytokines production and the… read more here.
Keywords: insulin; rnf41 expression; isg expression; expression ... See more keywords
Innate immune activation without immune cell infiltration in brains of murine models of Aicardi‐Goutières Syndrome
Sign Up to like & getrecommendations! Published in 2022 at "Brain Pathology"
DOI: 10.1111/bpa.13118
Abstract: Chronic inflammation is frequently invoked as a mechanism of neurodegeneration and yet inflammatory cell infiltrates are seldom seen in brains of these disorders. Different disciplines utilize different technologies and methodologies to describe what is immunologically… read more here.
Keywords: cell; immune cell; isg expression; pathology ... See more keywords
IFN‐stimulated Gene Expression, Type 2 Inflammation, and Endoplasmic Reticulum Stress in Asthma
Sign Up to like & getrecommendations! Published in 2018 at "American Journal of Respiratory and Critical Care Medicine"
DOI: 10.1164/rccm.201706-1070oc
Abstract: Rationale: Quantification of type 2 inflammation provided a molecular basis for heterogeneity in asthma. Non‐type 2 pathways that contribute to asthma pathogenesis are not well understood. Objectives: To identify dysregulated pathways beyond type 2 inflammation.… read more here.
Keywords: isg expression; stress; type inflammation; inflammation ... See more keywords