Generation of two human ISG15 knockout iPSC clones using CRISPR/Cas9 editing.
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DOI: 10.1016/j.scr.2020.102135
Abstract: Interferon stimulated gene 15 (ISG15) is one of the most highly upregulated proteins in response to viral infection and is involved in numerous pathways with multiple mechanisms of actions. ISG15 deficiency has been reported to… read more here.
Keywords: human isg15; two human; isg15 knockout; generation two ... See more keywords