METTL3‐Mediated m6A Modification of ISG15 mRNA Regulates Doxorubicin‐Induced Endothelial Cell Apoptosis
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DOI: 10.1111/jcmm.70339
Abstract: N6‐adenosine methylation (m6A) of RNA is involved in the regulation of various diseases. However, its role in chemotherapy‐related vascular endothelial injury has not yet been elucidated. We found that methyltransferase‐like 3 (METTL3) expression was significantly… read more here.
Keywords: induced endothelial; isg15 mrna; endothelial cell; isg15 ... See more keywords
ISG15 mRNA transcript level in circulating leucocytes prognostic of overall survival in hepatocellular carcinoma patients and correlated with quality of life disturbances involved in anorexia-cachexia
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DOI: 10.3389/fonc.2025.1589053
Abstract: Background An increasing number of immuno-therapeutic agents have proven efficacy in hepatocellular carcinoma (HCC). Inflammatory markers (c-reactive protein, interleukin-8 and inflammatory score) have been found to be prognostic factors in HCC patients. These inflammatory markers… read more here.
Keywords: transcript level; mrna transcript; isg15 mrna;