Mechanism of Interferon-Stimulated Gene Induction in HIV-1-Infected Macrophages
Sign Up to like & getrecommendations! Published in 2017 at "Journal of Virology"
DOI: 10.1128/jvi.00744-17
Abstract: ABSTRACT Viruses manipulate the complex interferon and interferon-stimulated gene (ISG) system in different ways. We have previously shown that HIV inhibits type I and III interferons in its key target cells but directly stimulates a… read more here.
Keywords: hiv; interferon; stimulated gene; induction ... See more keywords
Duck cGAS inhibits DNA and RNA virus replication by activating IFNs and antiviral ISGs
Sign Up to like & getrecommendations! Published in 2023 at "Frontiers in Immunology"
DOI: 10.3389/fimmu.2023.1101335
Abstract: Cyclic GMP-AMP Synthase (cGAS) is a pivotal adaptor of the signaling pathways involving the pattern recognition receptors and plays an important role in apoptosis and immune regulation. The cGAS function in mammals has been investigated… read more here.
Keywords: duck; replication; duck cgas; isgs ... See more keywords