Statin downregulation of miR-652-3p protects endothelium from dyslipidemia by promoting ISL1 expression.
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DOI: 10.1016/j.metabol.2020.154226
Abstract: BACKGROUND Aberrant endothelial function is a major contributing factor in cardiovascular disease. Dyslipidemia leads to decreased nitric oxide (NO) bioavailability, an early sign of endothelial failure. Low insulin gene enhancer protein (ISL1) levels decrease healthy… read more here.
Keywords: isl1 protein; isl1 expression; dyslipidemia; mir 652 ... See more keywords