Hydroxyurea Pharmacokinetics in Pediatric Patients After Total Pancreatectomy With Islet Autotransplantation.
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DOI: 10.1002/jcph.1759
Abstract: Total pancreatectomy with islet autotransplantation is a complex surgical approach for acute recurrent or chronic pancreatitis that frequently triggers extreme thrombocytosis (platelets ≥ 1000 × 109 /L). Thrombocytosis can be prothrombotic, so cytoreductive hydroxyurea is… read more here.
Keywords: hydroxyurea; total pancreatectomy; pancreatectomy islet; islet autotransplantation ... See more keywords
Is There a Benefit From Islet Autotransplantation in Patients With Type 1 Diabetes Mellitus Undergoing Total Pancreatectomy?
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DOI: 10.1097/mpa.0000000000002017
Abstract: ABSTRACT Children with acute recurrent and chronic pancreatitis (CP) experience abdominal pain that leads to hospitalizations, opioid dependence, and poor quality of life. Total pancreatectomy with islet autotransplantation (TPIAT) is offered as a surgical option… read more here.
Keywords: patients type; total pancreatectomy; islet autotransplantation; islet ... See more keywords
Urine Proteomics Reveals Sex-Specific Response to Total Pancreatectomy With Islet Autotransplantation
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DOI: 10.1097/mpa.0000000000002063
Abstract: Objectives Total pancreatectomy with islet autotransplantation (TPIAT) is a surgical option for refractory chronic pancreatitis-related pain. Despite the known clinical implications of TPIAT, the molecular effects remain poorly investigated. We performed the first hypothesis-generating study… read more here.
Keywords: tpiat; pancreatectomy islet; total pancreatectomy; islet autotransplantation ... See more keywords
Perioperative Coagulation Changes in Total Pancreatectomy and Islet Autotransplantation
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DOI: 10.1097/mpa.0000000000002085
Abstract: Objectives Thrombotic complications after total pancreatectomy with islet autotransplantation (TPIAT) are common. However, the systemic changes to coagulation in the perioperative period have not been well studied. Our objective was to evaluate the derangements in… read more here.
Keywords: coagulation; pancreatectomy islet; total pancreatectomy; islet autotransplantation ... See more keywords
Early use of continuous glucose monitoring in children and adolescents after total pancreatectomy with islet autotransplantation
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DOI: 10.1111/pedi.13168
Abstract: Children undergoing total pancreatectomy with islet autotransplantation (TPIAT) for chronic pancreatitis require intensive insulin therapy early after TPIAT with narrow glycemic targets, which can a present significant care burden. Outpatient use of continuous glucose monitoring… read more here.
Keywords: total pancreatectomy; pancreatectomy islet; islet autotransplantation; use continuous ... See more keywords
Predictors of Glycemic Outcomes at 1 Year Following Pediatric Total Pancreatectomy With Islet Autotransplantation.
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DOI: 10.2337/dc21-1222
Abstract: OBJECTIVE Total pancreatectomy with islet autotransplantation (TPIAT) is indicated to alleviate debilitating pancreas-related pain and mitigate diabetes in patients with acute recurrent and chronic pancreatitis when medical/endoscopic therapies fail. Our aim was to evaluate predictors… read more here.
Keywords: insulin requirement; insulin; year; total pancreatectomy ... See more keywords