Co‐microencapsulation of human umbilical cord‐derived mesenchymal stem and pancreatic islet‐derived insulin producing cells in experimental type 1 diabetes
Sign Up to like & getrecommendations! Published in 2020 at "Diabetes/Metabolism Research and Reviews"
DOI: 10.1002/dmrr.3372
Abstract: Post‐partum umbilical cord Wharton Jelly‐derived adult mesenchymal stem cells (hUCMS) hold anti‐inflammatory and immunosuppressive properties. Human pancreatic islet‐derived progenitor cells (hIDC) may de‐differentiate, and subsequently re‐differentiate into insulin producing cells. The two cell types share… read more here.
Keywords: pancreatic islet; umbilical cord; producing cells; islet derived ... See more keywords
Regenerating islet-derived protein 3-α is a prognostic biomarker for gastrointestinal chronic graft-versus-host disease
Sign Up to like & getrecommendations! Published in 2022 at "Blood Advances"
DOI: 10.1182/bloodadvances.2021005420
Abstract: Key Points Plasma levels of Reg3α were significantly increased in patients with GI-cGVHD compared with those without GI-cGVHD in 2 independent cohorts. Reg3α is a prognostic biomarker that identifies the likelihood of NRM in patients… read more here.
Keywords: biomarker; derived protein; prognostic biomarker; regenerating islet ... See more keywords
Four Decades After the Discovery of Regenerating Islet-Derived (Reg) Proteins: Current Understanding and Challenges
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DOI: 10.3389/fcell.2019.00235
Abstract: Regenerating islet-derived (Reg) proteins have emerged as multifunctional agents with pro-proliferative, anti-apoptotic, differentiation-inducing and bactericidal properties. Over the last 40 years since first discovered, Reg proteins have been implicated in a gamut of maladies including… read more here.
Keywords: reg proteins; islet derived; regenerating islet; biology ... See more keywords
Role of Regenerating Islet-Derived Protein 3A in Gastrointestinal Cancer
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DOI: 10.3389/fonc.2019.01449
Abstract: Regenerating islet-derived protein 3A (Reg3A), a protein mainly expressed in the digestive system, has been found over-expressed in many kinds of gastrointestinal cancer, including hepatocellular carcinoma, pancreatic cancer, gastric cancer, and colorectal cancer, therefore has… read more here.
Keywords: derived protein; islet derived; gastrointestinal cancer; regenerating islet ... See more keywords
Role of regenerating islet-derived proteins in inflammatory bowel disease
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DOI: 10.3748/wjg.v26.i21.2702
Abstract: Inflammatory bowel disease (IBD) is an inflammatory disorder of the gastrointestinal tract that affects millions of patients worldwide. It has a complex and multifactorial etiology leading to excessive exposure of intestinal epithelium to microbial antigens,… read more here.
Keywords: bowel disease; inflammatory bowel; islet derived; disease ... See more keywords