Three‐dimensional wet electrospun scaffold system for the differentiation of adipose‐derived mesenchymal stem cells to islet‐like clusters
Sign Up to like & getrecommendations! Published in 2022 at "Journal of Tissue Engineering and Regenerative Medicine"
DOI: 10.1002/term.3366
Abstract: Stem cell‐derived islet‐like clusters (ILCs) are an alternative source of pancreatic beta cells for the treatment of diabetic mellitus. An ideal 3D culture platform for the generation of ILCs of desired cluster size is a… read more here.
Keywords: islet like; wet electrospun; like clusters; scaffold ... See more keywords
Nanotopographical regulation of pancreatic islet-like cluster formation from human pluripotent stem cells using a gradient-pattern chip.
Sign Up to like & getrecommendations! Published in 2018 at "Acta biomaterialia"
DOI: 10.1016/j.actbio.2018.12.011
Abstract: Bioengineering approaches to regulate stem cell fates aim to recapitulate the in vivo microenvironment. In recent years, manipulating the micro- and nano-scale topography of the stem cell niche has gained considerable interest for the purposes… read more here.
Keywords: pancreatic islet; gradient pattern; islet like; stem ... See more keywords
Immune evasive human islet-like organoids ameliorate diabetes
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DOI: 10.1038/s41586-020-2631-z
Abstract: Islets derived from stem cells hold promise as a therapy for insulin-dependent diabetes, but there remain challenges towards achieving this goal 1 – 6 . Here we generate human islet-like organoids (HILOs) from induced pluripotent… read more here.
Keywords: islet; human islet; islet like; like organoids ... See more keywords
Three-dimensional bioprinting of functional β-islet-like constructs
Sign Up to like & getrecommendations! Published in 2023 at "International Journal of Bioprinting"
DOI: 10.18063/ijb.v9i2.665
Abstract: 256Diabetes is an autoimmune disease that ensues when the pancreas does not deliver adequate insulin or when the body cannot react to the existing insulin. Type 1 diabetes is an autoimmune disease defined by continuous… read more here.
Keywords: islet like; pancreatic islet; islet; three dimensional ... See more keywords