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Published in 2019 at "Advanced Science"
DOI: 10.1002/advs.201970036
Abstract: In article number 1801694, Junfeng Zhang, Chunming Wang, Lei Dong, and co‐workers biochemically remodel one of the two testicles of a mouse into a site that can protect xenogeneic islet cells from immune rejection. The…
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Keywords:
growing trans;
islet;
trans species;
transplantation growing ... See more keywords
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Published in 2018 at "Biotechnology and Bioengineering"
DOI: 10.1002/bit.26821
Abstract: Pancreatic islet transplantation is a promising alternative to whole‐pancreas transplantation as a treatment of type 1 diabetes mellitus. This technique has been extensively developed during the past few years, with the main purpose of minimizing…
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Keywords:
pancreatic islet;
islet;
islet transplantation;
transplantation ... See more keywords
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1
Published in 2022 at "Small"
DOI: 10.1002/smll.202202596
Abstract: Islet transplantation is a promising strategy for type 1 diabetes mellitus (T1DM) treatment, whereas implanted-associated foreign body reaction (FBR) usually induces the necrosis of transplanted islets and leads to the failure of glycemic control. Benefiting…
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Keywords:
zwitterion;
gelma;
foreign body;
islet transplantation ... See more keywords
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Published in 2017 at "Journal of Tissue Engineering and Regenerative Medicine"
DOI: 10.1002/term.1990
Abstract: The success of pancreatic islet (PI) transplantation is challenged by PI functional damage during the peritransplantation period. A silk‐based encapsulation platform including mesenchymal stromal cells (MSCs) was evaluated for islet cell delivery in vivo. Islet…
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Keywords:
pancreatic islet;
islet;
silk;
islet transplantation ... See more keywords
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Published in 2019 at "Current Diabetes Reports"
DOI: 10.1007/s11892-019-1145-2
Abstract: Purpose of reviewIn patients with type 1 diabetes with extreme glycemic variability, the restoration of pancreas endocrine function is potentially and completely achieved with islets of Langerhans (tissue derived from whole organ) or pancreas (whole…
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Keywords:
outcome driven;
islet transplantation;
transplantation;
transplantation alone ... See more keywords
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Published in 2019 at "Journal of Pharmaceutical Investigation"
DOI: 10.1007/s40005-019-00433-3
Abstract: Islet cell transplantation is a promising alternative for the treatment of type 1 diabetic mellitus which is caused by complete absence or reduced insulin production by pancreas. After Shapiro and his team carried out successful…
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Keywords:
hydrogels islet;
injectable hydrogels;
islet transplantation;
transplantation ... See more keywords
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Published in 2019 at "Acta biomaterialia"
DOI: 10.1016/j.actbio.2019.05.051
Abstract: The microvasculature in the pancreatic islet is highly specialized for glucose sensing and insulin secretion. Although pancreatic islet transplantation is a potentially life-changing treatment for patients with insulin-dependent diabetes, a lack of blood perfusion reduces…
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Keywords:
insulin;
islet;
vasculature islet;
islet transplantation ... See more keywords
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Published in 2020 at "Biomaterials"
DOI: 10.1016/j.biomaterials.2020.120499
Abstract: The subcutaneous space has been shown to be a suitable site for islet transplantation, however an abundance of islets is required to achieve normoglycemia, often requiring multiple donors. The loss of islets is due to…
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Keywords:
islet;
scalable device;
islet transplantation;
subcutaneous space ... See more keywords
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Published in 2018 at "Cytotherapy"
DOI: 10.1016/j.jcyt.2018.06.001
Abstract: BACKGROUND AIMS Adipose tissue-derived mesenchymal stromal cells (AT-MSCs), widely known as multipotent progenitors, release several cytokines that support cell survival and repair. There are in vitro and in vivo studies reporting the regenerative role of…
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Keywords:
islet;
islet transplantation;
transplantation;
adipose tissue ... See more keywords
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Published in 2022 at "Transplant immunology"
DOI: 10.1016/j.trim.2022.101579
Abstract: OBJECTIVE Podocyte injury has a critical role in the pathogenesis of diabetic nephropathy (DN). Microencapsulated islet transplantation (MIT) is identified as an effective method for improving the clinical condition of DN. This study aimed to…
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Keywords:
mit;
islet transplantation;
group;
podocyte injury ... See more keywords
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Published in 2022 at "Critical reviews in food science and nutrition"
DOI: 10.1080/10408398.2022.2098464
Abstract: The incidence of diabetes mellitus is dramatically increasing every year, causing a huge global burden. Moreover, existing anti-diabetic drugs inevitably bring adverse reactions, and the application of islet transplantation is often limited by the damage…
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Keywords:
transplantation;
mellitus islet;
diabetes mellitus;
effects anthocyanins ... See more keywords