Chronic Adrenergic Signaling Causes Abnormal RNA Expression of Proliferative Genes in Fetal Sheep Islets
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DOI: 10.1210/en.2018-00540
Abstract: Intrauterine growth restriction (IUGR) increases the risk of developing diabetes in later life, which indicates developmental programming of islets. IUGR fetuses with placental insufficiency develop hypoxemia, elevating epinephrine and norepinephrine (NE) concentrations throughout late gestation.… read more here.
Keywords: chronic adrenergic; islets chronic; expression; expressed genes ... See more keywords