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Abstract 503: ISM3412, a novel and selective MAT2A inhibitor for the treatment of cancer

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Published in 2023 at "Cancer Research"

DOI: 10.1158/1538-7445.am2023-503

Abstract: The enzyme methionine adenosyltransferase 2α (MAT2A) has an important role in metabolism and epigenetics as the major producer of the universal methyl donor S-adenosyl methionine (SAM). Despite broad cellular functions, MAT2A was recently implicated as… read more here.

Keywords: ism3412 novel; cancer; mat2a; mat2a inhibitor ... See more keywords