Site-Specific Radiohalogenation of a HER2-Targeted Single-Domain Antibody Fragment Using a Novel Residualizing Prosthetic Agent.
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DOI: 10.1021/acs.jmedchem.2c01331
Abstract: Because of their rapid tumor accumulation and normal tissue clearance, single-domain antibody fragments (sdAbs) are an attractive vehicle for developing radiotherapeutics labeled with the α-emitter 211At. Herein, we have evaluated iso-[211At]AGMB-PODS, a prosthetic agent that… read more here.
Keywords: single domain; domain antibody; pods 5f7ggc; agmb pods ... See more keywords