Electrochemical α-C(sp3)-H/O-H cross-coupling of isochromans and alcohols assisted by benzoic acid.
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DOI: 10.1039/d2cc03883h
Abstract: Isochroman moieties are present in a wide variety of biologically active molecules, but converting isochromans to α-substituted derivatives under mild conditions is challenging. Herein, we report a mild, convenient protocol for synthesis of α-alkoxy isochroman… read more here.
Keywords: cross coupling; electrochemical sp3; sp3 cross; isochromans alcohols ... See more keywords