1-Trifluoromethylisoquinolines from α-Benzylated Tosylmethyl Isocyanide Derivatives in a Modular Approach.
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DOI: 10.1021/acs.orglett.7b02882
Abstract: The preparation of various 1-trifluoromethylisoquinolines from α-benzylated tosylmethyl isocyanide derivatives and the commercial Togni reagent using a radical cascade is reported. The starting isocyanides are readily prepared in a modular sequence from commercial tosylmethyl isocyanide… read more here.
Keywords: trifluoromethylisoquinolines benzylated; isocyanide derivatives; benzylated tosylmethyl; derivatives modular ... See more keywords