Environmental and biological measurements of isoflurane and sevoflurane in operating room personnel
Sign Up to like & getrecommendations! Published in 2017 at "International Archives of Occupational and Environmental Health"
DOI: 10.1007/s00420-017-1287-y
Abstract: PurposeThe present study aimed to compare the concentration of isoflurane and sevoflurane in the individual’s breathing zone and ambient air of operating rooms (ORs), to investigate the correlation between breathing zone levels and urinary concentrations,… read more here.
Keywords: isoflurane sevoflurane; concentration isoflurane; air; sevoflurane ... See more keywords
Isoflurane and Sevoflurane Induce Cognitive Impairment in Neonatal Rats by Inhibiting Neural Stem Cell Development Through Microglial Activation, Neuroinflammation, and Suppression of VEGFR2 Signaling Pathway.
Sign Up to like & getrecommendations! Published in 2022 at "Neurotoxicity research"
DOI: 10.1007/s12640-022-00511-9
Abstract: Inhaled anesthetics are known to induce neurotoxicity in the developing brains of rodents, although the mechanisms are not well understood. The aim of this study was to elucidate the molecular mechanisms underlying anesthetics-induced neurodevelopmental toxicity… read more here.
Keywords: microglial activation; rats inhibiting; neural stem; isoflurane sevoflurane ... See more keywords
Sensitivity of inhalation anesthetics isoflurane and sevoflurane for the drug-induced QT-interval prolongation in guinea pigs.
Sign Up to like & getrecommendations! Published in 2020 at "Journal of pharmacological sciences"
DOI: 10.1016/j.jphs.2020.02.005
Abstract: We investigated effects of isoflurane and sevoflurane on sparfloxacin-induced QT-interval prolongation in guinea pigs under the monitoring of electrocardiogram and monophasic action potential (MAP), which was compared with those of halothane or non-inhaled anesthetics ketamine/xylazine.… read more here.
Keywords: isoflurane sevoflurane; prolongation guinea; induced interval; interval prolongation ... See more keywords
Cyclophilin D Modulates the Cardiac Mitochondrial Target of Isoflurane, Sevoflurane, and Desflurane
Sign Up to like & getrecommendations! Published in 2017 at "Journal of Cardiovascular Pharmacology"
DOI: 10.1097/fjc.0000000000000479
Abstract: Background: Volatile anesthetics are known to limit myocardial ischemia–reperfusion injuries. Mitochondria were shown to be major contributors to cardioprotection. Cyclophilin D (CypD) is one of the main regulators of mitochondria-induced cell death. We compared the… read more here.
Keywords: isoflurane sevoflurane; desflurane; cypd; sevoflurane desflurane ... See more keywords