Identification of an mRNA isoform switch for HNRNPA1 in breast cancers
Sign Up to like & getrecommendations! Published in 2021 at "Scientific Reports"
DOI: 10.1038/s41598-021-04007-y
Abstract: Roles of HNRNPA1 are beginning to emerge in cancers; however, mechanisms causing deregulation of HNRNPA1 function remain elusive. Here, we describe an isoform switch between the 3′-UTR isoforms of HNRNPA1 in breast cancers. We show… read more here.
Keywords: breast; isoform switch; breast cancers; isoform ... See more keywords
Integrated proteomics identifies troponin I isoform switch as a regulator of a sarcomere-metabolism axis during cardiac regeneration.
Sign Up to like & getrecommendations! Published in 2025 at "Cardiovascular research"
DOI: 10.1093/cvr/cvaf069
Abstract: AIMS Adult mammalian cardiomyocytes have limited regenerative potential, and after myocardial infarction (MI), injured cardiac tissue is replaced with fibrotic scar. In contrast, the neonatal mouse heart possesses a regenerative capacity governed by cardiomyocyte proliferation;… read more here.
Keywords: sarcomere metabolism; isoform switch; metabolism axis; metabolism ... See more keywords