Articles with "isoform usage" as a keyword



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Clustering of mRNA‐Seq data based on alternative splicing patterns

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Published in 2017 at "Biostatistics"

DOI: 10.1093/biostatistics/kxw044

Abstract: &NA; Sequencing of messenger RNA (mRNA) can provide estimates of the levels of individual isoforms within the cell. It remains to adapt many standard statistical methods commonly used for analyzing gene expression levels to take… read more here.

Keywords: clustering mrna; mrna seq; seq data; data based ... See more keywords
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Temporal Analysis of Gene Expression and Isoform Switching in Brown Bears (Ursus arctos).

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Published in 2022 at "Integrative and comparative biology"

DOI: 10.1093/icb/icac093

Abstract: Hibernation in brown bears is an annual process involving multiple physiologically distinct seasons - hibernation, active, and hyperphagia. While recent studies have characterized broad patterns of differential gene regulation and isoform usage between hibernation and… read more here.

Keywords: expression isoform; expression; isoform usage; gene expression ... See more keywords
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Genetic analysis of isoform usage in the human anti-viral response reveals influenza-specific regulation of ERAP2 transcripts under balancing selection.

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Published in 2018 at "Genome research"

DOI: 10.1101/gr.240390.118

Abstract: While genetic variants are known to be associated with overall gene abundance in stimulated immune cells, less is known about their effects on alternative isoform usage. By analyzing RNA-seq profiles of monocyte-derived dendritic cells from… read more here.

Keywords: erap2; response; balancing selection; gene ... See more keywords