Effect of Apolipoprotein E isoforms on the Abundance and Function of P-glycoprotein in Human Brain Microvascular Endothelial Cells
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DOI: 10.1007/s11095-024-03731-0
Abstract: Individuals with Alzheimer’s disease (AD) often require many medications; however, these medications are dosed using regimens recommended for individuals without AD. This is despite reduced abundance and function of P-glycoprotein (P-gp) at the blood-brain barrier… read more here.
Keywords: abundance; isoforms abundance; function; apoe isoforms ... See more keywords