A Paradoxical Effect of Interleukin-32 Isoforms on Cancer
Sign Up to like & getrecommendations! Published in 2022 at "Frontiers in Immunology"
DOI: 10.3389/fimmu.2022.837590
Abstract: IL-32 plays a contradictory role such as tumor proliferation or suppressor in cancer development depending on the cancer type. In most cancers, it was found that the high expression of IL-32 was associated with more… read more here.
Keywords: effect; role; paradoxical effect; cancer however ... See more keywords
p53 Isoforms as Cancer Biomarkers and Therapeutic Targets
Sign Up to like & getrecommendations! Published in 2022 at "Cancers"
DOI: 10.3390/cancers14133145
Abstract: Simple Summary The well-known tumor suppressor protein p53 plays important roles in tumor prevention through transcriptional regulation of its target genes. Reactivation of p53 activity has been a potent strategy for cancer treatment. Accumulating evidences… read more here.
Keywords: p53 isoforms; isoforms cancer; p53; cancer biomarkers ... See more keywords
Insulin Receptor Isoforms in Cancer
Sign Up to like & getrecommendations! Published in 2018 at "International Journal of Molecular Sciences"
DOI: 10.3390/ijms19113615
Abstract: The insulin receptor (IR) mediates both metabolic and mitogenic effects especially when overexpressed or in clinical conditions with compensatory hyperinsulinemia, due to the metabolic pathway resistance, as obesity diabetes. In many cancers, IR is overexpressed… read more here.
Keywords: cancer; receptor isoforms; isoforms cancer; insulin receptor ... See more keywords