Detection of truncated isoforms of human neuroserpin lacking the reactive center loop: Implications in noninhibitory role
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DOI: 10.1002/iub.2475
Abstract: Neuroserpin is a serine protease inhibitor expressed mainly in the brain and at low levels in other tissues like the kidney, testis, heart, and spinal cord. It is involved in the inhibition of tissue plasminogen… read more here.
Keywords: human neuroserpin; isoforms human; role; center loop ... See more keywords
Proteogenomics Integrating Novel Junction Peptide Identification Strategy Discovers Three Novel Protein Isoforms of Human NHSL1 and EEF1B2.
Sign Up to like & getrecommendations! Published in 2021 at "Journal of proteome research"
DOI: 10.1021/acs.jproteome.1c00373
Abstract: In eukaryotes, alternative pre-mRNA splicing allows a single gene to encode different protein isoforms that function in many biological processes, and they are used as biomarkers or therapeutic targets for diseases. Although protein isoforms in… read more here.
Keywords: protein; novel protein; novel junction; isoforms human ... See more keywords
Identification and characterization of new isoforms of human fas apoptotic inhibitory molecule (FAIM)
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DOI: 10.1371/journal.pone.0185327
Abstract: Fas Apoptosis Inhibitory Molecule (FAIM) is an evolutionarily highly conserved death receptor antagonist, widely expressed and known to participate in physiological and pathological processes. Two FAIM transcript variants have been characterized to date, namely FAIM… read more here.
Keywords: faim; faim faim; inhibitory molecule; isoforms human ... See more keywords