Genetic screens in isogenic mammalian cell lines without single cell cloning
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DOI: 10.1038/s41467-020-14620-6
Abstract: Isogenic pairs of cell lines, which differ by a single genetic modification, are powerful tools for understanding gene function. Generating such pairs of mammalian cells, however, is labor-intensive, time-consuming, and, in some cell types, essentially… read more here.
Keywords: single cell; cell cloning; cell lines; genetic screens ... See more keywords