One-pot synthesis of polycyclic isoindolines using isoindole umpolung
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DOI: 10.1016/j.tetlet.2020.152128
Abstract: Abstract Using an isoindole umpolung strategy, a one-pot synthesis of polycyclic isoindolines was accomplished. In this reaction, the in situ-generated nucleophilic isoindoles were converted to electrophilic isoindoliums via protonation, which underwent a Pictet-Spengler-type cyclization to… read more here.
Keywords: synthesis polycyclic; pot synthesis; polycyclic isoindolines; isoindole umpolung ... See more keywords