Base mediated spirocyclization of quinazoline: one-step synthesis of spiro-isoindolinone dihydroquinazolinones
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DOI: 10.1039/c9ra09567e
Abstract: A novel approach for the spiro-isoindolinone dihydroquinazolinones has been demonstrated from 2-aminobenzamide and 2-cyanomethyl benzoate in the presence of KHMDS as a base to get moderate yields. The reaction has been screened in various bases… read more here.
Keywords: base mediated; mediated spirocyclization; isoindolinone dihydroquinazolinones; spiro isoindolinone ... See more keywords