Articles with "isolate nuclei" as a keyword



A versatile and efficient method to isolate nuclei from low-input cryopreserved tissues for single-nuclei transcriptomics

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Published in 2025 at "Scientific Reports"

DOI: 10.1038/s41598-025-90070-8

Abstract: Clinical samples are vital for understanding diseases, but their scarcity requires refined research methods. Emerging single-cell technologies offer detailed views of tissue heterogeneity but need sufficient fully characterized tissues. We developed an optimized single-nuclei RNA… read more here.

Keywords: versatile efficient; isolate nuclei; efficient method; single nuclei ... See more keywords