Myeloid neoplasm with isolated del(5q) and the MPLW515L mutation fulfills the WHO diagnostic criteria for ET
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DOI: 10.1007/s12185-020-02872-3
Abstract: A 70-year-old male was referred to our hospital for marked thrombocytosis without anemia. The patient simultaneously presented with an MPL W515L mutation, one of the major driver mutations in essential thrombocythemia (ET), and deletion of… read more here.
Keywords: isolated del; del mplw515l; neoplasm isolated; myeloid neoplasm ... See more keywords
Clinical significance of isolated del(7p) in myeloid neoplasms.
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DOI: 10.1016/j.leukres.2017.01.016
Abstract: Sole del(7p) is a rare finding in myeloid neoplasms and its clinical significance is largely unknown. Here we report 10 patients with isolated del(7p), 4 had acute myeloid leukemia (AML), 2 myelodysplastic syndromes (MDS), 1… read more here.
Keywords: isolated del; del; myeloid neoplasms; del myeloid ... See more keywords
The significance of genetic mutations and their prognostic impact on patients with incidental finding of isolated del(20q) in bone marrow without morphologic evidence of a myeloid neoplasm
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DOI: 10.1038/s41408-020-0275-8
Abstract: Patients with a sole del(20q) chromosomal abnormality and without morphologic features of a myeloid neoplasm (MN) have shown variable clinical outcomes. To explore the potential risk stratification markers in this group of patients, we evaluated… read more here.
Keywords: isolated del; without morphologic; myeloid neoplasm; del 20q ... See more keywords
Myelodysplastic Syndromes with Isolated del(5q): Value of Molecular Alterations for Diagnostic and Prognostic Assessment
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DOI: 10.3390/cancers14225531
Abstract: Simple Summary Myelodysplastic syndromes with isolated del(5q) constitute the only MDS subtype defined by a cytogenetic alteration. The results of several clinical studies and the advances in new technologies have provided a better understanding of… read more here.
Keywords: del value; isolated del; myelodysplastic syndromes; mds isolated ... See more keywords