DystoniaBoTXNet: Novel Neural Network Biomarker of Botulinum Toxin Efficacy in Isolated Dystonia
Sign Up to like & getrecommendations! Published in 2022 at "Annals of Neurology"
DOI: 10.1002/ana.26558
Abstract: Isolated dystonia is characterized by abnormal, often painful, postures and repetitive movements due to sustained or intermittent involuntary muscle contractions. Botulinum toxin (BoTX) injections into the affected muscles are the first line of therapy. However,… read more here.
Keywords: novel neural; dystoniabotxnet novel; isolated dystonia; efficacy ... See more keywords
Genotype–Phenotype Relations for Isolated Dystonia Genes: MDSGene Systematic Review
Sign Up to like & getrecommendations! Published in 2021 at "Movement Disorders"
DOI: 10.1002/mds.28485
Abstract: This comprehensive MDSGene review is devoted to 7 genes — TOR1A, THAP1, GNAL, ANO3, PRKRA, KMT2B, and HPCA — mutations in which may cause isolated dystonia. It followed MDSGene's standardized data extraction protocol and screened… read more here.
Keywords: mutation carriers; hpca; dystonia; isolated dystonia ... See more keywords
A Critical Investigation of Cerebellar Associative Learning in Isolated Dystonia
Sign Up to like & getrecommendations! Published in 2022 at "Movement Disorders"
DOI: 10.1002/mds.28967
Abstract: Impaired eyeblink conditioning is often cited as evidence for cerebellar dysfunction in isolated dystonia yet the results from individual studies are conflicting and underpowered. read more here.
Keywords: isolated dystonia; cerebellar associative; investigation cerebellar; critical investigation ... See more keywords
Association of TOR1A and GCH1 Polymorphisms with Isolated Dystonia in India
Sign Up to like & getrecommendations! Published in 2020 at "Journal of Molecular Neuroscience"
DOI: 10.1007/s12031-020-01653-1
Abstract: Isolated dystonia is a common movement disorder often caused by genetic mutations, although it is predominantly sporadic in nature. Common variants of dystonia-related genes were reported to be risk factors for idiopathic isolated dystonia. In… read more here.
Keywords: associated isolated; dystonia; tor1a; isolated dystonia ... See more keywords
Chronic deep brain stimulation normalizes scalp EEG activity in isolated dystonia
Sign Up to like & getrecommendations! Published in 2018 at "Clinical Neurophysiology"
DOI: 10.1016/j.clinph.2017.11.011
Abstract: OBJECTIVE To investigate cortical activity using scalp EEG in patients with isolated dystonia treated with chronic deep brain stimulation (DBS), on and off stimulation. METHODS We analyzed 64-channel scalp EEG in 12 isolated dystonia patients… read more here.
Keywords: chronic deep; deep brain; stimulation; isolated dystonia ... See more keywords
Efficacy of pallidal stimulation in isolated dystonia: a systematic review and meta‐analysis
Sign Up to like & getrecommendations! Published in 2017 at "European Journal of Neurology"
DOI: 10.1111/ene.13255
Abstract: The aim of this review was to provide strong clinical evidence of the efficacy of deep brain stimulation (DBS) of the globus pallidus internus (GPi) in isolated inherited or idiopathic dystonia. Eligible studies were identified… read more here.
Keywords: stimulation; isolated dystonia; efficacy; review ... See more keywords
Flanker Task Performance in Isolated Dystonia (Blepharospasm): A Focus on Sequential Effects
Sign Up to like & getrecommendations! Published in 2020 at "Brain Sciences"
DOI: 10.3390/brainsci10020076
Abstract: Isolated dystonia manifests with involuntary muscle hyperactivity, but the extent of cognitive impairment remains controversial. We examined the executive functions in blepharospasm while accounting for motor symptom-related distractions as a factor often limiting the interpretability… read more here.
Keywords: task performance; patients blepharospasm; isolated dystonia; performance isolated ... See more keywords