BRAF status as a predictive factor for response in isolated limb perfusion
Sign Up to like & getrecommendations! Published in 2019 at "International Journal of Hyperthermia"
DOI: 10.1080/02656736.2019.1601778
Abstract: Abstract Background: Isolated limb perfusion (ILP) is a treatment option for unresectable in-transit melanoma metastases of the extremities. Approximately two-thirds of the patients have a complete response, and known predictive factors mainly regard tumor burden.… read more here.
Keywords: isolated limb; limb perfusion; braf v600e; response ... See more keywords
Addition of oncolytic virotherapy to clinical isolated limb perfusion for melanoma and sarcoma activates antitumor immunity
Sign Up to like & getrecommendations! Published in 2025 at "Journal for Immunotherapy of Cancer"
DOI: 10.1136/jitc-2025-012446
Abstract: Background We previously showed that oncolytic virotherapy delivered by isolated limb perfusion (ILP), combined with immune checkpoint inhibition, prevents both local tumor progression and systemic metastases in an animal sarcoma model. Methods We describe a… read more here.
Keywords: oncolytic virotherapy; virotherapy; isolated limb; melanoma ... See more keywords
Outcomes and Predictive Factors of Isolated Limb Infusion for Patients with In-transit Melanoma in China
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DOI: 10.1245/s10434-017-6256-x
Abstract: PurposeThis study was designed to evaluate the efficacy of isolated limb infusion (ILI) treatment in Chinese patients with in-transit melanoma and to identify factors predictive of the outcome.MethodsA total of 150 patients with in-transit melanoma… read more here.
Keywords: isolated limb; response; transit melanoma; limb infusion ... See more keywords