Pregnane neurosteroids exert opposite effects on GABA and glycine‐induced chloride current in isolated rat neurons
Sign Up to like & getrecommendations! Published in 2022 at "Hippocampus"
DOI: 10.1002/hipo.23449
Abstract: The ability of endogenous neurosteroids (NSs) with pregnane skeleton modified at positions C‐3 and C‐5 to modulate the functional activity of inhibitory glycine receptors (GlyR) and ionotropic ɣ‐aminobutyric acid receptors (GABAAR) was estimated. The glycine… read more here.
Keywords: peak amplitude; glycine; dhp; isolated rat ... See more keywords
Apium graveolens reduced phytofabricated gold nanoparticles and their impacts on the glucose utilization pattern of the isolated rat hemidiaphragm
Sign Up to like & getrecommendations! Published in 2022 at "Heliyon"
DOI: 10.1016/j.heliyon.2022.e08805
Abstract: The integration of nanotechnology with herbal medicines overcomes the limitations of herbal therapy and offers desirable bioactivity. Thus, this study was aimed at synthesizing Apium graveolens-gold nanoparticles (AG-AuNPs) and exploring their impact on the glucose… read more here.
Keywords: pattern isolated; apium graveolens; isolated rat; utilization pattern ... See more keywords
Integration of cardiac energetics, function and histology from isolated rat hearts perfused with doxorubicin and doxorubicin-ol; a model for use in drug safety evaluations.
Sign Up to like & getrecommendations! Published in 2018 at "Journal of pharmacological and toxicological methods"
DOI: 10.1016/j.vascn.2018.08.004
Abstract: The isolated rat heart (Langendorff) assay combined with NMR spectroscopy and histology were used to elucidate functional, metabolic, and histological signs of cardiotoxicity resulting from acute exposure to clinically relevant concentrations of doxorubicin and its… read more here.
Keywords: heart; isolated rat; spectroscopy; function ... See more keywords
Protective effects of glycine against diclofenac-induced toxicity in isolated rat hepatocytes.
Sign Up to like & getrecommendations! Published in 2025 at "Drug and chemical toxicology"
DOI: 10.1080/01480545.2025.2564433
Abstract: Diclofenac (DIC) is a common cyclo-oxygenase inhibitor that has been linked to liver toxicity. Alternatively, glycine (GLY) has several beneficial actions, including direct cytoprotective, anti-inflammatory, anti-apoptotic, and antioxidant effects. Hence, this study investigated the ability… read more here.
Keywords: rat; protective effects; diclofenac; isolated rat ... See more keywords
Effect of omentin on cardiovascular functions and gene expressions in isolated rat hearts
Sign Up to like & getrecommendations! Published in 2019 at "Anatolian Journal of Cardiology"
DOI: 10.14744/anatoljcardiol.2018.52333
Abstract: Objective: Omentin is a recently identified novel adipocytokine mainly expressed in the epicardial adipose tissue. Although it has favorable effects on cardiovascular disease, the impact of omentin on the hearts is still an understudied issue.… read more here.
Keywords: gene expressions; rat; isolated rat; rat hearts ... See more keywords
SkQ3 Exhibits the Most Pronounced Antioxidant Effect on Isolated Rat Liver Mitochondria and Yeast Cells
Sign Up to like & getrecommendations! Published in 2024 at "International Journal of Molecular Sciences"
DOI: 10.3390/ijms25021107
Abstract: Oxidative stress is involved in a wide range of age-related diseases. A critical role has been proposed for mitochondrial oxidative stress in initiating or promoting these pathologies and the potential for mitochondria-targeted antioxidants to fight… read more here.
Keywords: isolated rat; rat liver; oxidative stress; liver mitochondria ... See more keywords
Nandrolone Decanoate and Swimming Affects Cardiodynamic and Morphometric Parameters in the Isolated Rat Heart
Sign Up to like & getrecommendations! Published in 2022 at "Life"
DOI: 10.3390/life12081242
Abstract: (1) Background: The aim of this study was to show the effects of swimming and nandrolone administration on cardiodynamic and morphometric parameters of the isolated rat heart. (2) The study included 72 Wistar rats, divided… read more here.
Keywords: cardiodynamic morphometric; parameters isolated; heart; isolated rat ... See more keywords
Acute and Subacute Toxicity and Cytotoxicity of Opuntia Dillenii (Ker-Gawl) Haw. Seed Oil and Its Impact on the Isolated Rat Diaphragm Glucose Absorption
Sign Up to like & getrecommendations! Published in 2021 at "Molecules"
DOI: 10.3390/molecules26082172
Abstract: This study aims to assess the safety of the Opuntia dillenii (Ker-Gawl) haw. seed oil (ODSO) and its effect on the glucose absorption activity of the isolated rat hemidiaphragm. This oil’s safety was studied by… read more here.
Keywords: seed; safety; isolated rat; glucose absorption ... See more keywords
Coconut (Cocos nucifera (L.)) Water Improves Glucose Uptake with Concomitant Modulation of Antioxidant and Purinergic Activities in Isolated Rat Psoas Muscles
Sign Up to like & getrecommendations! Published in 2024 at "Plants"
DOI: 10.3390/plants13050665
Abstract: The present study investigated the effect of coconut water on glucose uptake and utilization, and metabolic activities linked to hyperglycemia in isolated rat psoas muscles. Coconut water was subjected to in vitro antioxidant and antidiabetic… read more here.
Keywords: psoas muscles; isolated rat; water; rat psoas ... See more keywords
Mechanical effects of ranolazine on normal and diabetic-isolated rat heart
Sign Up to like & getrecommendations! Published in 2021 at "Research in Pharmaceutical Sciences"
DOI: 10.4103/1735-5362.314825
Abstract: Background and purpose: Diabetic cardiomyopathy is a complication of diabetes defined as cardiac dysfunction without the involvement of pericardial vessels, hypertension, or cardiac valve disorders. Ranolazine, an antianginal drug, acts through blocking of cardiac late… read more here.
Keywords: normal diabetic; normal hearts; effects ranolazine; isolated rat ... See more keywords