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   Articles with "isolated rem" as a keyword



Deep Learning‐Based Neuromelanin MRI Changes of Isolated REM Sleep Behavior Disorder

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recommendations! Published in 2022 at "Movement Disorders"

DOI: 10.1002/mds.28933

Abstract: Isolated REM sleep behavior disorder (iRBD) is considered a prodromal stage of parkinsonism. Neurodegenerative changes in the substantia nigra pars compacta (SNc) in parkinsonism can be detected using neuromelanin‐sensitive MRI. read more here.

Keywords: isolated rem; sleep behavior; rem sleep; behavior disorder ... See more keywords

Patient Values and Preferences Regarding Prognostic Counseling in Isolated REM Sleep Behavior Disorder.

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recommendations! Published in 2022 at "Sleep"

DOI: 10.1093/sleep/zsac244

Abstract: STUDY OBJECTIVES Isolated REM sleep behavior disorder (iRBD) carries a high lifetime risk for phenoconversion to a defined neurodegenerative disease (NDD) including Parkinson disease, dementia with Lewy bodies, and multiple system atrophy. We aimed to… read more here.

Keywords: information; patient; prognostic counseling; values preferences ... See more keywords

1025 The Impact of Depression on Neurocognitive Functions and Conversion in Isolated REM Sleep Behavior Disorder

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recommendations! Published in 2024 at "SLEEP"

DOI: 10.1093/sleep/zsae067.01025

Abstract: Depression is frequently observed in patients with isolated REM sleep behavior disorder (iRBD). The aim of this study was to analyze cognitive function and quantified electroencephalography (QEEG) in iRBD patients according to the presence of… read more here.

Keywords: conversion; isolated rem; irbd; depression ... See more keywords

1274 Longitudinal Changes in Resting-state EEG in Isolated REM Sleep Behavior Disorder

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recommendations! Published in 2025 at "SLEEP"

DOI: 10.1093/sleep/zsaf090.1274

Abstract: Patients with isolated REM sleep behavior disorder (iRBD), a prodromal alpha-synucleinopathy, has been reported to show electroencephalographic (EEG) slowing compared to healthy controls. However, longitudinal studies examining brain activity changes in iRBD are scarce. This… read more here.

Keywords: rem sleep; mci; isolated rem; sleep behavior ... See more keywords

Objective autonomic testing in isolated REM sleep behavior disorder: a cornerstone for clinical practice, research, and trial design

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recommendations! Published in 2025 at "Sleep"

DOI: 10.1093/sleep/zsaf120

Abstract: The identification of objective, multimodal biomarkers for isolated REM sleep behavior disorder (iRBD) is one of the most pressing needs in the field of prodromal neurodegeneration. With iRBD increasingly recognized as a sentinel sign of… read more here.

Keywords: rem sleep; behavior disorder; isolated rem; sleep behavior ... See more keywords

Misfolded α-Synuclein Assessment in the Skin and CSF by RT-QuIC in Isolated REM Sleep Behavior Disorder

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recommendations! Published in 2023 at "Neurology"

DOI: 10.1212/wnl.0000000000207147

Abstract: Background and Objectives Real-time quaking-induced conversion (RT-QuIC) assay detects misfolded α-synuclein (AS) in the skin and CSF of patients with the synucleinopathies Parkinson disease and dementia with Lewy bodies. Isolated REM sleep behavior disorder (IRBD)… read more here.

Keywords: csf; skin csf; rem sleep; isolated rem ... See more keywords

99mTc-HMPAO SPECT Perfusion Signatures Associated With Clinical Progression in Patients With Isolated REM Sleep Behavior Disorder

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recommendations! Published in 2024 at "Neurology"

DOI: 10.1212/wnl.0000000000208015

Abstract: Background and Objectives Idiopathic/isolated REM sleep behavior disorder (iRBD) is associated with dementia with Lewy bodies and Parkinson disease. Despite evidence of abnormal cerebral perfusion in iRBD, there is currently no pattern that can predict… read more here.

Keywords: lewy bodies; isolated rem; perfusion; parkinson disease ... See more keywords

Association of Cardiovascular Autonomic Failure With Progression and Phenoconversion in Isolated REM Sleep Behavior Disorder

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recommendations! Published in 2025 at "Neurology"

DOI: 10.1212/wnl.0000000000213470

Abstract: Background and Objectives Isolated REM sleep behavior disorder (iRBD) is a prodromal state of α-synucleinopathies, presenting years before overt neurodegenerative disorders. Autonomic nervous system (ANS) involvement, particularly cardiovascular autonomic failure, may indicate progression. However, its… read more here.

Keywords: cardiovascular autonomic; phenoconversion; progression; isolated rem ... See more keywords

Fatigue in Patients with Idiopathic/Isolated REM Sleep Behavior Disorder

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recommendations! Published in 2022 at "Brain Sciences"

DOI: 10.3390/brainsci12121728

Abstract: Introduction: Fatigue is one of the most common and disabling symptoms of Parkinson’s Disease (PD). The occurrence and clinical features of fatigue in patients with prodromal PD remain largely elusive. This study aimed to investigate… read more here.

Keywords: idiopathic isolated; patients idiopathic; fatigue; motor ... See more keywords