Dimethyl Fumarate Delays Multiple Sclerosis in Radiologically Isolated Syndrome
Sign Up to like & getrecommendations! Published in 2022 at "Annals of Neurology"
DOI: 10.1002/ana.26555
Abstract: The radiologically isolated syndrome (RIS) represents the earliest detectable pre‐clinical phase of multiple sclerosis (MS). This study evaluated the impact of therapeutic intervention in preventing first symptom manifestation at this stage in the disease spectrum. read more here.
Keywords: isolated syndrome; radiologically isolated; fumarate delays; multiple sclerosis ... See more keywords
Changes in serum neurofilament light chain levels following narrowband ultraviolet B phototherapy in clinically isolated syndrome
Sign Up to like & getrecommendations! Published in 2022 at "Brain and Behavior"
DOI: 10.1002/brb3.2494
Abstract: To determine whether serum neurofilament light chain (sNfL) levels are suppressed in patients with the clinically isolated syndrome (CIS) following narrowband ultraviolet B phototherapy (UVB‐PT). read more here.
Keywords: light chain; serum neurofilament; clinically isolated; isolated syndrome ... See more keywords
Digital biomarkers can highlight subtle clinical differences in radiologically isolated syndrome compared to healthy controls
Sign Up to like & getrecommendations! Published in 2020 at "Journal of Neurology"
DOI: 10.1007/s00415-020-10276-w
Abstract: To explore the use of digital biomarkers to distinguish healthy controls (HC) from subjects with a radiologically isolated syndrome (RIS). We developed a smartphone application called MS Screen Test (MSST) to explore several dimensions of… read more here.
Keywords: radiologically isolated; healthy controls; ris subjects; isolated syndrome ... See more keywords
Drug Treatment of Clinically Isolated Syndrome
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DOI: 10.1007/s40263-019-00647-x
Abstract: Multiple sclerosis (MS) is an autoimmune disease of the central nervous system (CNS) that leads to inflammation, demyelination and ultimately axonal degeneration. In most cases, it is preceded by its precursor, clinically isolated syndrome (CIS)… read more here.
Keywords: treatment clinically; drug treatment; clinically isolated; disease ... See more keywords
Radiologically isolated syndrome in children: Current knowledge and future directions.
Sign Up to like & getrecommendations! Published in 2018 at "Multiple sclerosis and related disorders"
DOI: 10.1016/j.msard.2018.06.010
Abstract: As the use of magnetic resonance imaging (MRI) grows in clinical practice, clinicians are increasingly faced with the difficult task of interpreting the significance of incidental findings on brain MRI. Among individuals found to have… read more here.
Keywords: radiologically isolated; syndrome children; current knowledge; isolated syndrome ... See more keywords
Assessing cognitive performance in radiologically isolated syndrome.
Sign Up to like & getrecommendations! Published in 2019 at "Multiple sclerosis and related disorders"
DOI: 10.1016/j.msard.2019.04.030
Abstract: BACKGROUND Radiologically isolated syndrome (RIS) is defined as the occurrence of incidental brain MRI lesions suggestive of multiple sclerosis (MS) in otherwise healthy subjects without any signs or symptoms that could indicate to the disease.… read more here.
Keywords: radiologically isolated; age; cognitive performance; ris ... See more keywords
Multimodal peripheral fluid biomarker analysis in clinically isolated syndrome and early multiple sclerosis.
Sign Up to like & getrecommendations! Published in 2021 at "Multiple sclerosis and related disorders"
DOI: 10.1016/j.msard.2021.102809
Abstract: BACKGROUND Increasing evidence suggests that various inflammatory, immunological and metabolic pathways are altered in the clinically isolated syndrome (CIS) of multiple sclerosis (MS). Moreover, recent diagnostic criteria have made possible the very early diagnosis of… read more here.
Keywords: sclerosis; clinically isolated; analysis; isolated syndrome ... See more keywords
Clinically isolated syndrome: diagnosis and risk of developing clinically definite multiple sclerosis.
Sign Up to like & getrecommendations! Published in 2021 at "Neurologia"
DOI: 10.1016/j.nrl.2021.01.011
Abstract: INTRODUCTION In most cases, multiple sclerosis (MS) initially presents as clinically isolated syndrome (CIS). Differentiating CIS from other acute or subacute neurological diseases and estimating the risk of progression to clinically definite MS is essential… read more here.
Keywords: cis; risk; clinically definite; clinically isolated ... See more keywords
Inner retinal layer thinning in radiologically isolated syndrome predicts conversion to multiple sclerosis
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DOI: 10.1111/ene.14416
Abstract: Individuals with radiologically isolated syndrome (RIS) are at increased risk of converting to multiple sclerosis (MS). Early identification of later converters is crucial for optimal treatment decisions. The purpose of this study was to assess… read more here.
Keywords: radiologically isolated; inner retinal; conversion; isolated syndrome ... See more keywords
Evaluation of cognitive dysfunction by the clock drawing test in multiple sclerosis and clinically isolated syndrome patients: Correlation with other neuropsychological tests
Sign Up to like & getrecommendations! Published in 2022 at "Neurosciences"
DOI: 10.17712/nsj.2022.4.20220019
Abstract: Objectives: To evaluate the cognitive status with a simple practical test, clock drawing test (CDT), in a larger multiple sclerosis (MS) patient group and in comparison, with controls. Methods: We included 171 patients (17–65 years)… read more here.
Keywords: clock drawing; test; isolated syndrome; drawing test ... See more keywords
Cerebrospinal Fluid Findings in 541 Patients With Clinically Isolated Syndrome and Multiple Sclerosis: A Monocentric Study
Sign Up to like & getrecommendations! Published in 2021 at "Frontiers in Immunology"
DOI: 10.3389/fimmu.2021.675307
Abstract: Background Reports on typical routine cerebrospinal fluid (CSF) findings are outdated owing to novel reference limits (RL) and revised diagnostic criteria of Multiple Sclerosis (MS). Objective To assess routine CSF parameters in MS patients and… read more here.
Keywords: patients clinically; clinically isolated; csf; isolated syndrome ... See more keywords