Isolation, chemistry, and biology of pyrrolo[1,4]benzodiazepine natural products.
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DOI: 10.1002/med.21803
Abstract: The isolation of the antitumor antibiotic anthramycin in the 1960s prompted extensive research into pyrrolo[1,4]benzodiazepines (PBD) as potential therapeutics for the treatment of cancers. Since then, nearly 60 PBD natural products have been isolated and… read more here.
Keywords: natural products; pyrrolo; isolation chemistry; chemistry ... See more keywords