Isolation of infectious, non-fibrillar and oligomeric prions from a genetic prion disease
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DOI: 10.1093/brain/awaa078
Abstract: Gerstmann-Sträussler-Scheinker disease (GSS) is characterized by atypical N- and C-terminal cleaved protease-resistant PrPSc. Vanni et al. report that PrPSc oligomers purified from patients with GSS are authentic – but non-fibrillar – prions, thus uncovering the… read more here.
Keywords: isolation infectious; prion; non fibrillar; disease ... See more keywords