Low-background Acyl-biotinyl Exchange Largely Eliminates the Co-isolation of Non-S-acylated Proteins and Enables Deep S-acylproteomic Analysis.
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DOI: 10.1021/acs.analchem.9b01520
Abstract: Protein S-acylation (also called palmitoylation) is a common post-translational modification whose deregulation plays a key role in the pathogenesis of many diseases. Acyl-biotinyl exchange (ABE), a widely used method for the enrichment of S-acylated proteins,… read more here.
Keywords: acylated proteins; analysis; abe; non acylated ... See more keywords