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   Articles with "isolation stress" as a keyword



Prolonged isolation stress accelerates the onset of Alzheimer’s disease-related pathology in 5xFAD mice despite running wheels and environmental enrichment

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recommendations! Published in 2020 at "Behavioural Brain Research"

DOI: 10.1016/j.bbr.2019.112366

Abstract: Research has demonstrated that stress can exacerbate AD pathology in transgenic mouse models of AD. The purpose of the present studies was to extend this work by determining whether a social stressor, isolation stress, would… read more here.

Keywords: isolation stress; isolation; 5xfad mice; pathology ... See more keywords
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Activation of cannabinoid receptors elicits antidepressant-like effects in a mouse model of social isolation stress

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recommendations! Published in 2017 at "Brain Research Bulletin"

DOI: 10.1016/j.brainresbull.2017.01.018

Abstract: Social isolation stress (SIS) paradigm is a chronic stress procedure able to induce profound behavioral and neurochemical changes in rodents and evokes depressive and anxiety-like behaviors. Recent studies demonstrated that the cannabinoid system plays a… read more here.

Keywords: sis; social isolation; cannabinoid; isolation stress ... See more keywords
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Adolescent social isolation stress unmasks the combined effects of adolescent exercise and adult inflammation on hippocampal neurogenesis and behavior

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recommendations! Published in 2017 at "Neuroscience"

DOI: 10.1016/j.neuroscience.2017.09.020

Abstract: Hippocampal neurogenesis and associated cognitive behaviors are regulated by a number of factors including stress, inflammation, and exercise. However, the interplay between these factors remains relatively unexplored, especially across the lifespan. In the current study,… read more here.

Keywords: social isolation; neurogenesis; hippocampal neurogenesis; exercise ... See more keywords
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92 Intra-nasal oxytocin treatment does not attenuate the hypothalamo-pituitary-adrenal axis in beef heifers subjected to isolation stress or restraint and isolation stress

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recommendations! Published in 2019 at "Journal of Animal Science"

DOI: 10.1093/jas/skz122.097

Abstract: Changes in the physiological, psychological, and behavioral manifestations of stress are observed in association with increases in circulating oxytocin. Providing oxytocin intra-nasally attenuates stressor-induced hypothalamo-pituitary-adrenal (HPA) axis activation in humans and rodents. The present study… read more here.

Keywords: axis; isolation stress; stress; isolation ... See more keywords
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Social isolation stress favors cardiometabolic comorbidities of sleep apnea

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recommendations! Published in 2023 at "Physiology"

DOI: 10.1152/physiol.2023.38.s1.5731636

Abstract: Sleep apnea (SA) is a multifactorial and sex-specific respiratory disorder characterized by repeated respiratory arrests during sleep. However, the origins of this disease are not clearly identified. Chronic stress increases risk for obesity, hypertension, and… read more here.

Keywords: isolation stress; stress; sleep apnea; physiology ... See more keywords
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Effects of Importin α1/KPNA1 deletion and adolescent social isolation stress on psychiatric disorder-associated behaviors in mice

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recommendations! Published in 2021 at "PLoS ONE"

DOI: 10.1371/journal.pone.0258364

Abstract: Importin α1/KPNA1 is a member of the Importin α family widely present in the mammalian brain and has been characterized as a regulator of neuronal differentiation, synaptic functionality, and anxiety-like behavior. In humans, a de… read more here.

Keywords: isolation; social isolation; kpna1 deletion; isolation stress ... See more keywords

The Protective Effects of Crocin on Input-Output Functions and Long-term Potentiation of Hippocampal CA1 Area in Rats Exposed to Chronic Social Isolated Stress

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recommendations! Published in 2022 at "Basic and Clinical Neuroscience"

DOI: 10.32598/bcn.2022.2346.2

Abstract: Introduction: The lack of social communication is associated with the primary risk of proper brain functions. It is reported that crocin helps relieve this problem. The present study examined the protective effect of two doses… read more here.

Keywords: isolation stress; long term; stress; frontal cortex ... See more keywords