Articles with "isomerase" as a keyword



A novel thermotolerant l-rhamnose isomerase variant for biocatalytic conversion of d-allulose to d-allose

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Published in 2024 at "Applied Microbiology and Biotechnology"

DOI: 10.1007/s00253-024-13074-w

Abstract: Abstract A novel l -rhamnose isomerase was identified and cloned from an extreme-temperature aquatic habitat metagenome. The deduced amino acid sequence homology suggested the possible source of this metagenomic sequence to be Chloroflexus islandicus .… read more here.

Keywords: temperature; rhamnose isomerase; isomerase; allulose allose ... See more keywords

Identification of amphioxus protein disulfide isomerase as both an enzyme and an immunocompotent factor.

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Published in 2021 at "Developmental and comparative immunology"

DOI: 10.1016/j.dci.2021.104238

Abstract: Previous studies have shown that protein disulfide isomerase (PDI), a member of the thioredoxin (TRX) superfamily, are broadly associated in immune responses in a variety of animals. However, it remains largely unknown about the direct… read more here.

Keywords: immunocompotent factor; disulfide isomerase; protein disulfide; isomerase ... See more keywords

Characterization of a recombinant l-ribose isomerase from Mycetocola miduiensis and its application for the production of l-ribulose.

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Published in 2020 at "Enzyme and microbial technology"

DOI: 10.1016/j.enzmictec.2020.109510

Abstract: An enzyme, l-ribose isomerase (l-RI), mostly catalyzes the isomerization of l-ribose and l-ribulose. These so-called rare sugars are essential for the treatment of cancer and other viral diseases. In the present study, l-ribose isomerase produced… read more here.

Keywords: isomerase; mycetocola miduiensis; recombinant ribose; ribose isomerase ... See more keywords

Rational design of Shewanella sp. l-arabinose isomerase for d-galactose isomerase activity under mesophilic conditions.

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Published in 2021 at "Enzyme and microbial technology"

DOI: 10.1016/j.enzmictec.2021.109796

Abstract: d-Tagatose, a potential low calorific substitute for sucrose, can be produced by bioconversion of d-galactose catalysed by l-arabinose isomerase. l-Arabinose isomerase from Shewanella sp. ANA-3 is unique for its ability to catalyse bioconversion reactions under… read more here.

Keywords: arabinose isomerase; activity; isomerase; mesophilic conditions ... See more keywords

Aconitate isomerase from maize leaves: Light-dependent expression and kinetic properties.

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Published in 2020 at "Journal of plant physiology"

DOI: 10.1016/j.jplph.2020.153350

Abstract: Aconitate isomerase (EC 5.3.3.7) interconverts cis- and trans-isomers of aconitic acid. Expression of the gene encoding this enzyme was studied in maize (Zea mays L.) leaves depending on light regime. Aconitate isomerase was induced by… read more here.

Keywords: aconitate isomerase; trans aconitate; maize leaves; isomerase ... See more keywords

Developing a new drug against trichomoniasis, new inhibitory compounds of the protein triosephosphate isomerase.

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Published in 2020 at "Parasitology international"

DOI: 10.1016/j.parint.2020.102086

Abstract: Trichomonas vaginalis is the protozoan parasite responsible for the most prevalent, non-viral, sexually transmitted disease, which affects millions of people around the world. The main treatment against this disease is metronidazole and some other nitroimidazole… read more here.

Keywords: developing new; trichomoniasis; new drug; isomerase ... See more keywords

Novel Recyclable UCST-Type Immobilized Glucose Isomerase Biocatalyst with Excellent Performance for Isomerization of Glucose to Fructose.

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Published in 2022 at "Journal of agricultural and food chemistry"

DOI: 10.1021/acs.jafc.2c05667

Abstract: The development of a suitable immobilization strategy to improve the performance of immobilized glucose isomerase for the isomerization of glucose to fructose is crucial to promoting the industrial production of high-fructose syrup. In this work,… read more here.

Keywords: isomerization glucose; isomerase biocatalyst; immobilized glucose; glucose isomerase ... See more keywords

Identification and functional expression of a new xylose isomerase from the goat rumen microbiome in Saccharomyces cerevisiae.

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Published in 2022 at "Letters in applied microbiology"

DOI: 10.1111/lam.13689

Abstract: The current climate crisis demands replacement of fossil energy sources with sustainable alternatives. In this scenario, second-generation bioethanol, a product of lignocellulosic biomass fermentation, represents a more sustainable alternative. However, Saccharomyces cerevisiae cannot metabolize pentoses,… read more here.

Keywords: xylose isomerase; identification functional; isomerase; goat rumen ... See more keywords

Borrelial phosphomannose isomerase as a cell surface localized protein that retains enzymatic activity and promotes host-pathogen interaction

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Published in 2025 at "mBio"

DOI: 10.1128/mbio.03609-24

Abstract: ABSTRACT All organisms produce an intracellular Zn2+-dependent enzyme, phosphomannose isomerase (PMI) or mannose-6 phosphate isomerase, that catalyzes the reversible conversion of mannose-6-phosphate and fructose-6-phosphate during sugar metabolism and polysaccharide biosynthesis. Unexpectedly, we discovered an additional… read more here.

Keywords: bbpmi; host; isomerase; culture ... See more keywords

Mechanism of Erastin-Induced Ferroptosis in MDA-MB-231 Human Breast Cancer Cells: Evidence for a Critical Role of Protein Disulfide Isomerase

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Published in 2022 at "Molecular and Cellular Biology"

DOI: 10.1128/mcb.00522-21

Abstract: Ferroptosis is a form of regulated cell death resulting predominantly from catastrophic accumulation of lipid reactive oxygen species (ROS). While the antioxidant systems that counter ferroptosis have been well characterized, the mechanism underlying ferroptosis-associated accumulation… read more here.

Keywords: lipid ros; mda 231; accumulation; accumulation lipid ... See more keywords

Xylose fermentation efficiency of industrial Saccharomyces cerevisiae yeast with separate or combined xylose reductase/xylitol dehydrogenase and xylose isomerase pathways

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Published in 2019 at "Biotechnology for Biofuels"

DOI: 10.1186/s13068-019-1360-8

Abstract: BackgroundXylose isomerase (XI) and xylose reductase/xylitol dehydrogenase (XR/XDH) pathways have been extensively used to confer xylose assimilation capacity to Saccharomyces cerevisiae and tackle one of the major bottlenecks in the attainment of economically viable lignocellulosic… read more here.

Keywords: xylitol dehydrogenase; reductase xylitol; saccharomyces cerevisiae; xdh ... See more keywords