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Published in 2019 at "FEBS Letters"
DOI: 10.1002/1873-3468.13718
Abstract: Ecdysteroids are critically important for the formation of the insect exoskeleton. Cholesterol is a precursor of ecdysone and its active form 20‐hydroxyecdysone, but some steps in the ecdysteroid biosynthesis pathway remain unknown. An essential requirement…
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Keywords:
isomerase activity;
biosynthesis;
transferase;
ecdysteroid biosynthesis ... See more keywords
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Published in 2021 at "Biochemistry and Biophysics Reports"
DOI: 10.1016/j.bbrep.2021.101078
Abstract: The common marmoset Callithrix jacchus encodes two glutathione transferase (GST) enzymes with ketosteroid double-bond isomerase activity. The most active enzyme is CjaGST A3-3 showing a specific activity with 5-androsten-3,17-dione (Δ5-AD) of 62.1 ± 1.8 μmol…
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Keywords:
isomerase activity;
cjagst;
ketosteroid isomerase;
activity ... See more keywords